36 citations
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January 2014 in “The Journal of Sexual Medicine” This study found that transdermal testosterone significantly increased the frequency of satisfactory sexual events in women experiencing SSRI/SNRI-related loss of libido, but did not improve overall sexual self-rating scores.
March 2020 in “European Journal of Pediatric Dermatology” This article highlights that isotretinoin can rarely cause persistent sexual dysfunction, similar to finasteride and certain antidepressants, a side effect not mentioned in the drug’s data sheet.
54 citations
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May 2018 in “International journal of risk & safety in medicine” This study observed enduring sexual dysfunction reported in 300 cases globally following the use of SSRIs, finasteride, and isotretinoin, with common symptoms like genital anaesthesia and loss of libido.
11 citations
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April 2023 in “Annals of General Psychiatry” This study found that males treated with serotonergic antidepressants had an increased risk of erectile dysfunction, with an adjusted odds ratio of 3.2, and the risk for post-SSRI sexual dysfunction was 0.46%, emphasizing the importance of informed consent due to these potential irreversible side effects.
4 citations
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April 2020 in “Reports of Practical Oncology & Radiotherapy” This review discusses the role of mental healthcare in managing sexual side effects of prostate cancer radiotherapy and highlights the importance of patient education and psychological support for improved quality of life.