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research Dietary measures as an adjunctive therapy in alopecia areata: a scoping review

January 2025 in “Clinical and Experimental Dermatology”

In this review, researchers investigated 14 articles on how various dietary measures may influence hair regrowth by possibly reducing intestinal and skin inflammation in patients with alopecia areata.

A Minor Research Project Entitled: To Measure the Presence of Various Secondary Metabolites in Basil Oil

research A MINOR RESEARCH PROJECT ENTITLED-" TO MEASURE THE PRESENCE OF VARIOUS SECONDARY METABOLITIES IN BASIL OIL

May 2026

This source explores the diverse benefits of basil oil, highlighting its use in aromatherapy for stress relief, as a remedy for skin and respiratory issues, and in traditional medicine for its antiseptic and anti-inflammatory properties.

research Androgenic Alopecia and Stress-Induced Premature Senescence by Cumulative Ultraviolet Light Exposure

27 citations , January 2002 in “Exogenous Dermatology”

In this study, researchers reported that chronic UV exposure may contribute to androgenic alopecia progression by influencing hair cycle changes and exacerbating solar elastosis in the scalp.

research FORMULATION AND EVALUATION OF PERIWINKLE HAIR SERUM

September 2026 in “World Journal of Pharmacy and Pharmaceutical Sciences”

This study reports the successful formulation of a stable herbal hair serum with Catharanthus roseus extract and other ingredients, noting it has a suitable pH, consistency, and stability, suggesting potential effectiveness as a natural alternative for hair care pending further clinical trials.

research Protection against oxidative damage and anti-inflammatory effect of melatonin in scald rat

January 2008

In scalded rats, this study found that early melatonin administration may reduce oxidative stress and inflammation, thus protecting hair follicle cells after severe burns.

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community Reducing Fibrosis in Hair Loss: Topical Pirfenidone

59 upvotes 5 months ago

Topical pirfenidone is highlighted as an effective anti-inflammatory and anti-fibrotic treatment for hair loss, particularly in addressing perifollicular fibrosis, which may enhance the effectiveness of standard treatments like finasteride and minoxidil. The user also uses calcipotriol, MCT oil, ciclopirox shampoo, and benzoyl peroxide shampoo as part of their regimen.

community Ketoconazole shampoo has worked great for me. Those looking to take preventative measures should consider it.

in Ketoconazole 178 upvotes 1 year ago

Ketoconazole shampoo helps reduce hair shedding and improve thickness for some, but can cause dryness or irritation. Its effectiveness compared to finasteride or minoxidil varies among users.

community Would taking Ketoconazole 2% shampoo before signs of male pattern baldness help delay hair loss?

in Research/Science 7 upvotes 2 years ago

The conversation is about a user considering the use of Ketoconazole 2% shampoo before showing signs of male pattern baldness (MPB) to potentially delay its onset, inspired by a YouTuber who uses the shampoo to reduce scalp DHT levels. The user's interest in this preventative measure stems from a family history of MPB.

community Minoxidil and concern about cats

5 upvotes 1 year ago

Minoxidil is highly toxic to cats, and even small amounts can be fatal. The user decided against using topical minoxidil due to the risk to their cats and considered oral minoxidil and ketoconazole shampoo as alternatives.

community My derm said they came up with a new serum that is better then fin? What’s y’all’s thoughts

7 months ago

A new serum claims to enhance hair regrowth by amplifying oxygen delivery, improving the effectiveness of treatments like exosomes and peptides. Users are skeptical, questioning its efficacy compared to established treatments like Minoxidil and Finasteride.

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Learn

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learn Overview

learn Epidermal Growth Factor

learn Thymosin Beta 4

learn Cetirizine

What makes cetirizine a unique anti-inflammatory option for your scalp? Laboratory work reports that cetirizine lowers PGD2 and other inflammatory mediators, which is why researchers have proposed it for the scalp. There is no approved topical product and the clinical evidence is one small unblinded pilot study in pattern hair loss, so scalp use is off-label and experimental.

learn Low Level Laser Therapy

laser therapy for anti-inflammatory and likely insignificant hair regrowth effects

learn Metformin

diabetes drug with anti-inflammatory, immunomodulatory, and insulin-sensitizing properties

learn Centella

Sensitive to hormones? A centella scalp mask may help ease hidden inflamm Centella asiatica has anti-inflammatory and wound-healing effects in animal and cell studies, but no published research has tested a centella scalp mask on the human scalp, in hormonal contexts or otherwise, and no community reports were found of one being used this way.

learn procapil

Tried everything and still getting bald patches? Procapil may help calm the immune response Procapil is a cosmetic ingredient complex; laboratory studies of its individual ingredients report anti-inflammatory effects, but no published clinical trial has tested it in alopecia areata or any other immune-related hair loss. Spreading bald patches should be assessed by a dermatologist.

learn Baicapil

Struggling with patchy hair loss like alopecia areata? Baicapil might help by reducing inflammation and reactivating growth. There is no published trial of Baicapil in alopecia areata. The anti-inflammatory and hair-density claims come from the ingredient's manufacturer and from laboratory work on its plant extracts, in people with androgenetic-type hair loss rather than autoimmune patchy hair loss.

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