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The Role of Androgens in Androgenetic Alopecia Associated with the Severity of COVID-19

research O papel dos andrógenos na alopecia androgenética associada à gravidade do COVID-19

July 2022 in “Conjeturas”

This review explores the role of androgens in both SARS-CoV-2 infection severity and the development of alopecia, concluding that androgens influence hair growth cycles and promote alopecia.

Study of the Expression of Androgen, Estrogen, and Progesterone Receptors in Patients With Frontal Fibrosing Alopecia

research Estudio de la expresión de receptores de andrógenos, estrógenos y progesterona mediante inmunohistoquímica en pacientes con alopecia frontal fibrosante

March 2023 in “Revista médica Clínica Las Condes”

This study observed a tendency for patients with frontal fibrosing alopecia to have more androgen receptors in their scalp than healthy controls, though this difference was not statistically significant.

Influence of Intestinal Microbiota Imbalances on Androgenetic and Areata Alopecia: A Narrative Literature Review

research INFLUÊNCIA DOS DESEQUILÍBRIOS DA MICROBIOTA INTESTINAL NAS ALOPECIAS ANDROGENÉTICA E AREATA: Uma revisão narrativa da literatura

October 2025 in “Scientia Generalis”

In this narrative review, dysbiosis was found to potentially influence androgen metabolism and immune response, suggesting that gut microbiota balance may play a role in the prevention and treatment of androgenetic and areata alopecia.

Role of Peptide Growth Factors in the Rhythm of Hair Change

research Role of peptide growth factors in the rhythm of change hair

June 2015 in “Vestnik dermatologii i venerologii”

This review discusses the role of growth factors in hair physiology and their involvement in conditions like androgynous and focal alopecia, reporting no new clinical findings.

research Study of the structural-mechanical properties of cream with minoxidil

January 2016

This study found that a 2% minoxidil cream for androgenous alopecia maintained optimal rheological properties for consistent application and long-term stability.

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Learn

7 / 801 results

learn Alopecia Areata

autoimmune disorder causing patchy hair loss

learn Alfatradiol

Does Alfatradiol work the same for women, men, and trans people? Almost all controlled data on topical alfatradiol comes from cisgender women, where it slowed hair loss rather than regrowing hair and was outperformed by minoxidil. No published controlled trial covers cisgender men, and none covers trans people at all — so the honest answer is that the difference has not been measured.
Alfatradiol: What does a form of estrogen have to do with hair loss in men? Alfatradiol (17α-estradiol) is a prescription topical hormone, licensed for androgenetic alopecia in Germany but not FDA-approved. The controlled trial evidence is in women, where it produced stabilisation rather than regrowth and was outperformed by minoxidil; no comparable placebo-controlled trial in men appears to have been published.

learn TDM-105795

What types of alopecia or hair loss conditions might TDM-105795 be designed to target based on current research? TDM-105795 may target non-scarring alopecia, particularly androgenetic alopecia.

learn GT20029

research compound made to degrade androgen receptors in scalp

Is GT20029 safe and effective for both men and women with androgenic alopecia? Not yet. GT20029 is an experimental drug: early trials suggest it is well tolerated, but its effectiveness and long-term safety are unproven, especially in women.

learn Finasteride

Frontline, gold standard treatment for combatting androgenic alopecia

Does hair strand thickness decrease in men with androgenic alopecia? Can finasteride help restore it? Androgenic alopecia thins hair strands by miniaturizing follicles. The pivotal finasteride trials (1,553 men, 1 mg/day, two years) report increased hair counts and improved assessed appearance, but they measured density, not the diameter of individual strands, so the effect on thickness itself is not established.

learn Ketoconazole

antifungal with some anti-androgenic benefits, often used as a shampoo

learn Nanoxidil

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Community Join

5 / 24 results

community (MTF 35) Results of 18 Months of HRT

775 upvotes 8 months ago

A transgender woman experienced significant hair regrowth after 18 months of hormone replacement therapy (HRT) with estrogen and bicalutamide. The discussion notes HRT's effectiveness for hair regrowth but warns against its use for cisgender men due to feminizing effects.

community 200 days on dut + min, what do you think?

599 upvotes 11 months ago

The user reports significant hair regrowth after 200 days using dutasteride and minoxidil, attributing changes to hair dye. Others doubt the authenticity and discuss treatment effectiveness and side effects.

community The meds work: my dad at 23 yo vs me at 35 yo

1791 upvotes 1 year ago

Finasteride and oral minoxidil effectively maintain a youthful appearance and full head of hair, despite genetic predispositions to balding. The discussion also considers the impact of DHT blockers on masculinity and aging, with lifestyle choices like sunscreen use and a vegetarian diet mentioned.

community Anybody else obsessively searching for pp405 and counting the days?

69 upvotes 1 year ago

People are eagerly awaiting the release of PP405, a new hair loss treatment. Some are using minoxidil and finasteride in the meantime, but there are concerns about scams and unverified products.

community Solving Hair Loss with Research at MIT

in Research/Science 595 upvotes 1 year ago

Hair loss treatments like minoxidil, finasteride, TDM-105795, and PP405. MIT is hosting a hackathon to find innovative hair loss solutions.

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