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research Androgen levels and apoptosis in the testis during postnatal development of finasteride-treated male rat offspring

10 citations , September 2015 in “Folia Histochemica Et Cytobiologica”

This study found that paternal exposure to finasteride in male rats may impair fertility and affect androgen-sensitive spermatogenesis in their male offspring.

research Restoration of Spermatogenesis and Male Fertility Using an Androgen Receptor Transgene

15 citations , March 2015 in “PloS one”

This study demonstrated that an AR-EGFP transgene can restore AR function and fertility in Sertoli cell-specific AR knockout mice, highlighting its potential use in understanding androgen receptor functions.

research Physiology of the Hypothalamic Pituitary Gonadal Axis in the Male

70 citations , March 2016 in “Urologic Clinics of North America”

This article reviews the coordination of the hypothalamic-pituitary-gonadal axis, male fertility, and therapies for hypogonadism, but reports no new clinical findings.

Male Gonadal Function in Coeliac Disease: Sex Hormones

research Male gonadal function in coeliac disease: 2. Sex hormones.

69 citations , February 1983 in “Gut”

This study found that untreated men with coeliac disease exhibited androgen resistance, potentially linked to sexual dysfunction, which improved as intestinal health improved, a pattern not observed in other chronic illnesses.

research A Review of Androgen‐Progestin Regimens for Male Contraception

43 citations , July 2003 in “Andrology”

This review evaluates previous studies on androgen-progestin combinations for male contraception, concluding that long-acting injectable formulations appear promising due to their effectiveness and minimal short-term adverse effects.

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learn Stem Cell Factor

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community If we lose hair because of our sensitivity to DHT, then why are we trying to reduce DHT when our sensitive androgen receptors are the culprit?

13 upvotes 4 years ago

The conversation discusses the effectiveness of reducing DHT for hair loss treatment and explores alternative approaches like reducing androgen receptor sensitivity. Specific treatments mentioned include finasteride, dutasteride, pyrilutamide (KX-826), GT20029, and RU58841.

community Sebaceous filaments / blackheads on scalp - are they a cause of MPB or a symptom?

in Research/Science 1 upvotes 1 month ago

Sebaceous filaments or blackheads on the scalp are not a cause of hair loss; it's more likely due to hormonal factors, particularly in androgen-sensitive areas like the temples and crown. The user is using topical finasteride, minoxidil, and tretinoin for treatment.

community Affordable anti androgens in India?

in Treatment 4 upvotes 1 year ago

The conversation discusses hair loss treatments, specifically the use of anti-androgens like RU58841 and Pyrilutamide, which are expensive in India. Alternatives like spironolactone and concerns about the effectiveness of finasteride and dutasteride are also mentioned.

community Topicals for sensitive scalp (+sed derm)

9 upvotes 2 months ago

The conversation is about finding a gentle topical treatment for a sensitive scalp with seborrheic dermatitis. Suggestions include using Trichosol/Trichofoam-based topical finasteride/minoxidil, which is considered gentle on the scalp.

community Research: Minoxidil grows hair by suppressing androgen activity (DHT) in hair follicles.

43 upvotes 6 years ago

Minoxidil may suppress androgen activity in hair follicles, potentially aiding in hair growth and prostate cancer treatment. Users discuss the effectiveness of minoxidil and finasteride for hair maintenance and regrowth, with some preferring topical applications over oral due to safety concerns.

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