22 citations
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July 1990 in “Acta Dermato Venereologica” In this study, high concentrations of dihydrotestosterone and testosterone reduced the growth of human hair follicle cells in vitro, while high estradiol levels increased their growth.
7 citations
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June 1967 in “Journal of Investigative Dermatology” This study reports an unusual finding of plucked anagen hairs with intact hair papilla and connective tissue sheath in various scalp disorders, suggesting further documentation is needed.
December 2010 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” This entry does not provide an abstract or new research findings, so no specific results are available for summary.
This study found that testosterone and dihydrotestosterone significantly decreased the proliferation of papilla cells compared to dermal fibroblasts and outer root sheath keratinocytes in cultured hair follicle cells.
April 2017 in “Journal of Investigative Dermatology” This study observed that a 3D culture model of hair follicle cells showed an anagen-like phase between days 3 to 6 and transitioned to a catagen-like phase by day 7, highlighting cell differentiation and structural development over time.