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This study observed that Ptprq mutant mice exhibit significant abnormalities in hair bundle structure and vestibular dysfunction, suggesting similar issues may contribute to hearing loss and vestibular problems in humans with PTPRQ mutations.

The Naked gene in mice causes abnormal sebaceous glands and disrupts hair follicle organization.

This study found that hucMSC-EXOs delivered via intratympanic injection effectively target vestibular sensory tissues, significantly reducing gentamicin-induced balance issues and high-frequency hearing loss, with some measured outcomes surpassing those achieved with dexamethasone.

Pre-natal, internal, and external factors may contribute to the development of Autism Spectrum Disorder (ASD).