Search

for
Search:

Research

5 / 1000+ results

Synthesis and 5α-Reductase Inhibitory Activity of 8-Substituted Benzo[ƒ]Quinolinones Derived from Palladium Mediated Coupling Reactions

research Synthesis and 5α-reductase inhibitory activity of 8-substituted benzo[ƒ]quinolinones derived from palladium mediated coupling reactions

14 citations , February 1998 in “Bioorganic & Medicinal Chemistry Letters”

This study explored how modifying the 8-substituent of 8-bromobenzoquinolinone affects its selectivity in inhibiting both 5 alpha-reductase isozymes in the scalp.

research Process Development and Crystallization in Oiling-Out System of a Novel Topical Antiandrogen

9 citations , January 2017 in “Organic Process Research & Development”

This article describes the efficient synthesis of (S)-N-(2-bromo-6-methoxypyridin-4-yl)-2-hydroxy-2,4-dimethylpentanamide, a novel topical antiandrogen, with high purity and enantiomeric excess but reports no pharmacological results.

FeCl3-Catalyzed C-N Coupling Reaction Between Cyclic Ethers and Heterocyclic Amines

research FeCl3-catalysed C-N coupling reaction between cyclic ethers and heterocyclic amines

4 citations , December 2014 in “European Journal of Chemistry”

This study synthesized and characterized new 2-hydroxypyrrolidine/piperidine derivatives using FeCl₃·6H₂O as a catalyst, but it reports no biological or clinical results.

research Kisspeptin and LH pulsatile temporal coupling in PCOS patients

49 citations , May 2018 in “Endocrine”

This study found that only eumenorrheic polycystic ovary syndrome patients showed a temporal coupling between kisspeptin and luteinizing hormone pulsatile secretions.

research Polarity signaling ensures epidermal homeostasis by coupling cellular mechanics and genomic integrity

38 citations , July 2019 in “Nature Communications”

This study found that Par3 plays a crucial role in maintaining epidermal homeostasis by regulating Rho/actomyosin contractility and ensuring mitotic accuracy, with potential implications for other self-renewing epithelia.

View more "amide coupling" in research →

Community Join

3 / 1000+ results

community Hair loss treatment tier list by Dr Oscar Muñoz

932 upvotes 2 years ago

Dr. Oscar Muñoz's hair loss treatment tier list suggests oral minoxidil and finasteride are highly effective, while topical treatments like RU58841 and microneedling are less effective. Users discuss the effectiveness of various treatments, with some favoring oral options for their practicality and higher response rates.

community Meds aside, what do you guys use to thicken hair

9 upvotes 2 months ago

The conversation is about temporary hair thickening solutions, with suggestions including volumizing mousse, sea salt spray, Aveda thickening paste, tinted dry shampoo, and cold water rinses. The user is already using oral Minoxidil, Dutasteride, and keto shampoo, and has had a hair transplant.

community Tips/Advice on current situation aside from shaving bald

1 upvotes 5 years ago

The user experienced worse hair after removing a wig system and has been using Hairband 82 Comfort Flex, Hair Max supplements, dermarolling, and a scalp massager for 4 months without clear results. They are hesitant to use Minoxidil due to shedding concerns and avoid finasteride due to side effects, preferring Saw Palmetto instead.

View more "amide coupling" in community →

Learn

— no results

Try a deeper search in learn →

Experts

— no results

Try a deeper search in experts →

Clinics

— no results

Try a deeper search in clinics →