November 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that engineered high-affinity soluble CD200R agonists, including ARQ-234, showed superior efficacy in reducing immune responses in various preclinical models of inflammatory conditions, suggesting potential as a therapeutic for atopic dermatitis and other related diseases.
4 citations
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November 2024 in “Cell Biology and Toxicology” This study suggests that targeting olfactory receptors in the lung epithelium might help treat odorant-induced asthma in cases without type 2 inflammation, as these receptors could play a role in airway sensitivity to smells.
1 citations
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January 2026 in “International Journal of Dermatology” In this study, a case of dissecting cellulitis of the scalp was reported in a man after starting dupilumab therapy, highlighting potential immune pathways involved and the importance of recognizing such paradoxical inflammatory reactions to prevent irreversible alopecia.
3 citations
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December 2021 in “Physiological Research” This review discusses the potential link between androgen deficiency and increased COVID-19 severity in aging men, but reports no new clinical results; it suggests that low testosterone levels may pose a risk factor.
108 citations
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July 2004 in “American Journal of Pathology” This study suggests that nerve growth factor plays a crucial role in the stress-induced termination of hair growth in mice, and its antagonism might offer a therapeutic approach to mitigate stress-related hair loss.