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    GlossaryAgouti Signaling Protein

    protein influencing hair color by inhibiting melanocortin 1 receptor

    Agouti Signaling Protein (ASIP) is a protein that plays a crucial role in determining hair color in mammals. It works by inhibiting the action of the melanocortin 1 receptor (MC1R), which leads to the production of yellow or red pigments (pheomelanin) instead of black or brown pigments (eumelanin). This protein is also involved in various biological processes, including energy metabolism and obesity.

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