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research Infrared and Raman Diagnostic Modeling of Phosphate Adsorption on Ceria Nanoparticles

21 citations , October 2023 in “The Journal of Physical Chemistry C”

This study used theoretical calculations to show that phosphates strongly bind to cerium dioxide surfaces in various stable configurations, with spectral signatures identifiable in the infrared and Raman spectra, informing future experimental efforts in controlling the enzymatic activity of ceria nanoparticles.

research Evaluation of the Hairless Rat as a Model for in Vivo Percutaneous Absorption

37 citations , January 1997 in “Journal of Pharmaceutical Sciences”

This study observed that hairless rat skin was more permeable to mannitol and progesterone than hairy rat skin, indicating that follicular structures significantly impact percutaneous absorption.

research Absorption Capability of a 645-nm Diode Laser on Swine Soft Tissue Samples: a Preliminary Study in an Ex-Vivo Model Tissue Samples: a Preliminary Study in an Ex-Vivo Mo

1 citations , August 2019 in “Journal of Dentistry Indonesia”

This ex vivo study reported that a 645-nm wavelength red-light laser can penetrate and reach cells in the various layers of swine oral mucosa and periosteum tissue samples.

research Simultaneous effects of tocopheryl polyethylene glycol succinate (TPGS) on local hair growth promotion and systemic absorption of topically applied minoxidil in a mouse model

18 citations , October 2005 in “International Journal of Pharmaceutics”

This study found that incorporating 0.5% TPGS into topical minoxidil solutions enhanced hair growth in mice, although increasing TPGS to 2% decreased effectiveness.

research The risk of hydroquinone and sunscreen over-absorption via photodamaged skin is not greater in senescent skin as compared to young skin: Nude mouse as an animal model

18 citations , May 2014 in “International journal of pharmaceutics”

This study found that UVA and UVB exposure increased hydroquinone and sunscreen absorption in nude mouse skin, with less absorption enhancement observed in more lipophilic sunscreens.

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Community Join

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community Could coffee contribute to hair loss?

4 upvotes 4 years ago

Coffee may negatively impact hair health due to its vasoconstrictor effects, potential to increase DHT, and interference with nutrient absorption. There is no strong clinical evidence linking caffeine to hair loss or regrowth in humans, but moderation is advised.

community Rubedo Life Sciences Announces Clinical Study to Treat Hair Loss with GPX4 Modulator RLS-1496, First Human Ex Vivo Evidence Demonstrates Robust Hair Follicle Growth

1071 upvotes 1 week ago

Rubedo Life Sciences is developing a GPX4 modulator, RLS-1496, for hair loss treatment, showing promising hair follicle growth in early tests. Concerns include potential side effects like organ damage, with a realistic market release several years away.

community Natural sweetener Stevia found to turbocharge male pattern baldness treatment: Mice given Stevia patch had 18 times better absorption of minoxidil and hair coverage of 67.5% in bald areas after just 35 days.

1741 upvotes 9 months ago

Stevia microneedles increased minoxidil absorption and hair growth in mice. The conversation humorously questions the applicability of these results to humans.

community deeper understanding of microneedling

16 upvotes 3 years ago

Microneedling can enhance hair growth by increasing drug absorption and activating stem cells, with different needle depths serving distinct purposes. Users report success with microneedling, often in combination with treatments like minoxidil and finasteride, and emphasize waiting periods for topical application to avoid side effects.

community Tretinoin every other day? (with daily minoxidil)

in Minoxidil 1 upvotes 1 year ago

The user is considering using Tretinoin every other day alongside daily Minoxidil to manage hair loss and is concerned about inconsistent absorption affecting regrowth. They have noticed a significant reduction in shedding but are unsure if it's due to Tretinoin or the end of the Minoxidil/finasteride shedding phase.

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Learn

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learn Tretinoin

Vitamin A retinoid cream, prescribed for acne

learn Neem Oil

Oil from the neem tree, used in traditional remedies

learn oleic acid

Does Oleic Acid improve absorption of other topical hair treatments? In lab studies, oleic acid helps some drugs pass through skin. This has not been shown to improve hair-loss results in people.

learn Vitamin C

Can Vitamin C improve the absorption of other hair-supporting nutrients? Vitamin C increases absorption of non-heme iron, which may matter when shedding is linked to iron deficiency. There is no good evidence that it boosts absorption of other hair-related nutrients.

learn retinol

Can retinol help enhance the absorption of ingredients like minoxidil or peptides? No human study has measured whether retinol increases scalp absorption of minoxidil or peptides. Retinoids thicken rather than thin the epidermis, and they can irritate skin and need caution in pregnancy.

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