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Glossary Adipose-Derived Stem Cells

stem cells harvested from fat tissue for regenerative purposes

Adipose-Derived Stem Cells (ADSCs) are stem cells that are harvested from fat tissue. These cells have the ability to differentiate into various cell types, including bone, cartilage, and muscle cells, making them valuable for regenerative medicine and tissue engineering. They are also being researched for their potential in treating conditions like alopecia, as they can promote hair growth and repair damaged hair follicles.

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research Therapeutic and Clinical Potential of Adipose-Derived Stem Cell Secretome for Skin Regeneration

2 citations , November 2025 in “Cells”

This review presents evidence supporting the potential of adipose-derived stem cell secretome as a promising cell-free therapy for skin repair, emphasizing its application in wound healing, alopecia, skin rejuvenation, and inflammatory skin diseases.

research Adipose-derived Stem Cell Secretome and Its Potential Role in the Treatment of Androgenetic Alopecia

October 2021 in “Plastic and reconstructive surgery. Global open”

This study found that levels of certain signaling proteins were significantly higher in the alopecia zone compared to other areas, suggesting a role in androgenetic alopecia etiology.

research Different levels of EGF, VEGF, IL‐6, MCP‐1, MCP‐3, IP‐10, Eotaxin and MIP‐1α in the adipose‐derived stem cell secretome in androgenetic alopecia

1 citations , February 2022 in “Experimental Dermatology”

This study found that the secretory profiles of adipose-derived stem cells vary between balding and non-balding scalp areas in androgenetic alopecia patients, suggesting involvement of angiogenic and inflammatory processes in the condition's development.

Hair Regeneration in Androgenetic Alopecia Using Secretome of Adipose-Derived Stem Cells and Minoxidil: A Comparative Study of Three Groups

research Hair Regeneration in Androgenetic Alopecia using Secretome of Adipose-derived Stem Cells (ADSC) and Minoxidil: A Comparative Study of Three Groups

April 2024

This study found that treatments with adipose-derived stem cell secretome and minoxidil significantly improved hair growth in androgenetic alopecia, with the combination therapy showing the greatest improvement over 12 weeks.

research Stem cell secretome as a mechanism for restoring hair loss due to stress, particularly alopecia areata: narrative review

2 citations , October 2022 in “Journal of Biomedical Science”

This review discusses the potential of secretome derived from stem cells for treating alopecia areata and reports no new clinical results; the authors suggest the need for further human trials.

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community New Hair Loss Treatment: Adipose Derived Secretomes

18 upvotes 1 year ago

Adipose-derived stem cell secretome showed significant improvement in hair density and growth, especially when combined with minoxidil, suggesting a synergistic effect. The study had limitations, including a small sample size and potential bias.

community My progress with various products and without oral fin or oral dut on 17 months

in Progress Pictures 62 upvotes 1 year ago

The user shared their hair loss treatment progress using topical products like exosomes, fluridil, Kx826, and topical dutasteride, avoiding oral finasteride and dutasteride due to side effects. They found exosomes from Creative Biolabs most effective and also used topical probiotics, noting improvements without significant side effects.

community Promising stem cell treatment

4 upvotes 6 years ago

A promising stem cell treatment for hair loss using adipose-derived stem cell conditioned medium is discussed. Users express interest in the treatment's cost and effectiveness, noting impressive results from a 2015 study.

community Hair growth stimulated by allogenic adipose-derived stem cells supplemented with ATP in a mouse model of dihydrotestosterone-induced androgenetic alopecia

41 upvotes 1 year ago

Adipose-derived stem cells with ATP improved hair regrowth in male and female mice with androgenetic alopecia. The most effective treatments were low dose stem cells with ATP for males and medium dose stem cells with non-liposomal ATP for females.

community Il PP405 è molto promettente ma non è l'unico in grado di liberarci dalla iattura

3 upvotes 1 year ago

PP405 shows promise in hair loss treatment, but stem cell therapy using adipose-derived stem cells and ATP also successfully reversed androgenetic alopecia in mice. Stem cell therapy is costly, and some doubt the effectiveness of PP405 based on press releases.

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