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Clinical Exome Sequencing Unveils the Genetic Landscape of Polycystic Ovarian Syndrome Focusing on Lean and Obese Phenotypes: Implications for Cost-Effective Diagnosis and Personalized Treatment

research Clinical Exome Sequencing Unveils the Genetic Landscape of Polycystic Ovarian Syndrome Focusing on Lean and Obese Phenotypes: Implications for Cost-Effective Diagnosis and Personalized Treatment

June 2024 in “Research Square (Research Square)”

Young women in West Bengal, India, with PCOS often have estrogen resistance, leptin receptor issues, folate deficiency, T2DM, and acanthosis, commonly linked to obesity.

research Discovery of a Transdermally Deliverable Pentapeptide for Activating AdipoR1 to Promote Hair Growth

8 citations, September 2021 in “EMBO Molecular Medicine”

A new small peptide may help hair growth by activating a specific receptor and should be tested in humans.

research Hair Growth-Promoting Effects of Adiponectin In Vitro

22 citations, June 2012 in “Journal of Investigative Dermatology”

Adiponectin may stimulate hair growth and could be a potential treatment for promoting hair growth.

Kojyl Cinnamate Ester Derivatives Increase Adiponectin Expression and Stimulate Adiponectin-Induced Hair Growth Factors in Human Dermal Papilla Cells

research Kojyl Cinnamate Ester Derivatives Increase Adiponectin Expression and Stimulate Adiponectin-Induced Hair Growth Factors in Human Dermal Papilla Cells

9 citations, April 2019 in “International Journal of Molecular Sciences”

Kojyl cinnamate ester derivatives can promote hair growth by increasing adiponectin production in fat tissues.

research Wound Healing Impairment in Type 2 Diabetes Model of Leptin-Deficient Mice: A Mechanistic Systematic Review

10 citations, August 2022 in “International Journal of Molecular Sciences”

Leptin-deficient mice, used as a model for Type 2 Diabetes, have delayed wound healing due to impaired contraction and other dysfunctional cellular responses.

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community The Big Fat Layer II

in Research/Science 26 upvotes 4 years ago

Hair loss treatment should target dermal white adipose tissue (DWAT) to restore hair follicles. Potential remedies include tocopherol (vitamin E), botox, rosiglitazone, niacin, kojyl cinnamate esters, and ADP355.