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Sequential Cyclic Changes of Hair Roots Revealed by Dermoscopy Demonstrate a Progressive Mechanism of Diffuse Alopecia Areata Over Time

research Sequential cyclic changes of hair roots revealed by dermoscopy demonstrate a progressive mechanism of diffuse alopecia areata over time

4 citations , October 2018 in “Experimental Dermatology”

This study suggests that diffuse alopecia areata initially involves an intense inflammatory attack during the anagen phase, progressing through different hair cycle stages with specific shedding patterns.

research Histopathology of alopecia areata, acute and chronic: Why is it important to the clinician?

43 citations , May 2011 in “Dermatologic Therapy”

This article discusses the phases and histological features of alopecia areata and reports no new clinical findings; the authors emphasize recognizing these phases for accurate diagnosis.

research Alopecia areata incognita: True or false?

19 citations , December 2008 in “Journal of The American Academy of Dermatology”

This study suggests that yellow dots observed in scalp videodermoscopy are not highly specific to alopecia areata, as they appear in various types of alopecia.

research Hair Loss after Rhytidectomy

July 2004 in “Dermatologic Surgery”

This study identified acute localized telogen effluvium as a potential cause of temporal hair loss following rhytidectomy.

research Permanent chemotherapy-induced nonscarring alopecia and premature ovarian failure

5 citations , March 2015 in “Clinical and Experimental Dermatology”

This case report describes a 22-year-old woman who developed persistent, non-scarring hair loss and premature ovarian failure following a myeloablative umbilical cord transplant for acute myeloid leukemia.

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Community Join

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community My story: Trying to halt diffuse hair loss for past couple of years but got acute hair fall after quitting minoxidil and finasteride on my dermatologist recommendation

9 upvotes 1 year ago

A 22-year-old man experienced significant hair loss after stopping minoxidil and finasteride, causing emotional distress. He resumed these treatments and is considering dutasteride and microneedling to manage his hair loss.

community Everything you ever wanted to know about Pelage Pharma's PP405: how it works and what to expect

126 upvotes 3 months ago

PP405 may encourage earlier hair growth and slightly increase visible hair count but does not reverse hair follicle miniaturization in male pattern baldness. It does not address damage to the dermal papilla or broken Wnt signaling.

community Reminder: NURTURE those dormant hair follicles for as long as you can until PP405 comes out in 2028-2030

in Treatment 191 upvotes 9 months ago

PP405 is anticipated as a future treatment for dormant hair follicles, but its effectiveness and safety are uncertain. Current treatments include oral minoxidil and microneedling, with some avoiding finasteride due to side effects.

community Accelerated Hair Loss from Creatine

137 upvotes 10 months ago

Creatine may cause hair loss in some individuals, especially those on finasteride, despite no scientific link. Personal experiences suggest individual sensitivity to DHT could be a factor.

community "Creatine causes hair loss" myth debunked once and for all

22 upvotes 3 years ago

Creatine does not directly cause hair loss but may increase DHT levels, potentially worsening hair loss in those predisposed to male pattern baldness. Users have mixed experiences, with some reporting increased shedding and others seeing no effect.

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Learn

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learn Osteopontin

signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

learn Neem Oil

natural substance from Neem tree with medicinal and pesticidal properties

learn Hair Transplant

When will I see results from a hair transplant? Full results from a hair transplant are typically visible between 9 and 18 months.
How long do hair transplants last? Hair transplants are typically permanent, but surrounding hair may thin over time.
When can I exercise after a hair transplant? Avoid strenuous exercise for at least 1 month after a hair transplant.

learn Fluridil

Can daily Fluridil application stop hair follicle miniaturization? The single published fluridil trial (43 men, 9 months, double-blind and placebo-controlled) reported more hairs in the growth phase, but it never measured follicle diameter and has not been replicated — so whether daily use stops miniaturization is unproven, and community users describe stabilization rather than regrowth.

learn Finasteride

Does hair strand thickness decrease in men with androgenic alopecia? Can finasteride help restore it? Androgenic alopecia thins hair strands by miniaturizing follicles. The pivotal finasteride trials (1,553 men, 1 mg/day, two years) report increased hair counts and improved assessed appearance, but they measured density, not the diameter of individual strands, so the effect on thickness itself is not established.

learn Scalp Micropigmentation

scalp tattoos to mimic the appearance of light stubble

learn Microneedling

technique to create small wounds in skin to activate collagen production and hair growth

learn Hair Fibers

cosmetic product that temporarily makes hair appear thicker

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SMP Specialist
Hairo Fallas
Newark, NJ, United States

Hairo Fallas