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Glossary Activin

protein regulating cell growth and hair follicle development

Activin is a protein that plays a crucial role in regulating various biological processes, including cell growth, inflammation, and hormone secretion. It is particularly important in the context of hair biology, as it can influence hair follicle development and cycling, potentially impacting conditions like alopecia.

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Research

5 / 723 results

research Activin B Promotes BMSC-Mediated Cutaneous Wound Healing by Regulating Cell Migration via the JNK—ERK Signaling Pathway

45 citations , April 2013 in “Cell Transplantation”

In this study, the researchers reported that activin B combined with bone marrow-derived mesenchymal stem cells enhanced wound healing and hair follicle regeneration in rats by promoting cell migration through the ERK and JNK pathways.

research Activin B Promotes Epithelial Wound Healing In Vivo through RhoA-JNK Signaling Pathway

38 citations , September 2011 in “PLOS ONE”

This study found that activin B promotes epithelial wound healing in mice through the RhoA-Rock-JNK-cJun signaling pathway, suggesting a potential therapeutic role for activin B in wound repair.

research Activin B Stimulates Mouse Vibrissae Growth and Regulates Cell Proliferation and Cell Cycle Progression of Hair Matrix Cells through ERK Signaling

23 citations , February 2019 in “International Journal of Molecular Sciences”

This study found that Activin B at 10 ng/mL may promote vibrissae follicle growth in mice by enhancing hair matrix cell proliferation and cell cycle progression via ERK signaling pathways.

research Activin B Promotes Initiation and Development of Hair Follicles in Mice

5 citations , January 2013 in “Cells Tissues Organs”

This study found that activin B promotes the initiation and development of hair follicles in both cultured and neonatal mouse skin models.

research Supplementary Material for: Activin B Promotes Initiation and Development of Hair Follicles in Mice

January 2013

This study found that activin B promotes the initiation and development of hair follicles in cultured and neonatal mice.

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Community Join

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community [30M] Regenera Activ (7 Weeks) + Topical Dutasteride/Minoxidil (12 Weeks)

in Progress Pictures 187 upvotes 1 year ago

A 30-year-old man shared his positive experience with hair regrowth using Regenera Activ, topical Dutasteride, Minoxidil, and PRP over 12 weeks. He plans to continue with injectable Dutasteride and emphasizes the importance of starting treatment early to combat hair loss.

community How do people afford finasteride/dutasteride?

in Treatment 27 upvotes 2 years ago

People discuss the high cost of brand name finasteride and dutasteride, suggesting generics as cheaper alternatives. They share prices from various regions, highlighting significant cost differences.

community 10 month meds progress before/after

81 upvotes 4 months ago

A user shared their 10-month progress using finasteride, minoxidil foam, occasional microneedling, Regenera Activa, and exosomes for hair loss, reporting no side effects. They occasionally use Nizoral shampoo for a dry scalp.

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Learn

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learn Follistatin

glycoprotein that inhibits TGF-β and promotes hair growth by antagonizing activin

What is follistatin, and how does it influence hair follicle growth and regeneration? Follistatin blocks activin and related growth-inhibiting proteins, which in laboratory and animal work is described as keeping hair follicles in their growth phase; the only verifiable human evidence is a single small 2011 phase 1 injection trial, so follistatin remains experimental and is not an approved hair-loss treatment.
Are there any clinical studies supporting follistatin as a hair loss treatment? There is no controlled human trial showing follistatin treats hair loss; the published work is mouse and laboratory biology on the activin/follistatin signalling system, plus one small 2011 phase 1 injection study of a combination product, so follistatin remains experimental and unapproved.

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