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5 / 32 resultslearn Fluridil
a topical anti-androgen with less systemic involvement
learn Caffeine
the stimulant you know and love can be used topically to stimulate hair
learn Bicalutamide
a nonsteroidal anti-androgen, most commonly used orally for women
learn Cyproterone
a synthetic anti-androgen and weak progestogen that inhibits DHT binding to androgen receptor
Research
5 / 1000+ results![Function and interactions of the Ysc84/SH3yl1 family of actin- and lipid-binding proteins](/images/research/1c4d44f9-be7a-4510-9bee-f0351e417d79/small/19689.jpg)
research Function and interactions of the Ysc84/SH3yl1 family of actin- and lipid-binding proteins
The Ysc84/SH3yl1 protein family is important for cell movement and the process of taking in materials by interacting with actin and cell membranes.
![364 Mechanical forces of human dermal fibroblasts significantly decrease with age](/images/research/6a3886ad-ccf9-4aeb-9819-8bdab6d3260e/small/12669.jpg)
research 364 Mechanical forces of human dermal fibroblasts significantly decrease with age
Skin cell strength decreases significantly as we age.
![Comparative Proteomic Analysis in Scar-Free Skin Regeneration in Acomys cahirinus and Scarring Mus musculus](/images/research/e7cab679-9454-4fa0-ad05-223dfea57549/small/12675.jpg)
research Comparative Proteomic Analysis in Scar-Free Skin Regeneration in Acomys cahirinus and Scarring Mus musculus
The African spiny mouse heals skin without scarring due to different protein activity compared to the common house mouse, which heals with scarring.
![The role of tight junctions in skin barrier function and dermal absorption](/images/research/d5534e78-0bf6-4015-aca5-1cfb769bf1f3/small/35275.jpg)
research The role of tight junctions in skin barrier function and dermal absorption
Tight junctions are key for skin protection and controlling what gets absorbed or passes through the skin.
![DHT and E2 synthesis-related proteins and receptors expression in male yak skin during different hair follicle stages](/images/research/5b3634b2-116d-4f00-9481-3b1599941965/small/12117.jpg)
research DHT and E2 synthesis-related proteins and receptors expression in male yak skin during different hair follicle stages
Male yak hair growth is influenced by DHT synthesis, which is promoted by 5α-red1 and AR during growth phases, while E2 may inhibit growth through ERα.
Community Join
5 / 1000+ resultscommunity FCE 28260: A Forgotten 5α-Reductase Inhibition
FCE 28260 (PNU 156765), an under-explored 5α-reductase inhibitor, showcases promising results in research by Giudici et al., outperforming well-known treatments like Finasteride in reducing the conversion of testosterone to DHT. Its superior efficacy, demonstrated through lower IC50 values in both natural and human recombinant enzyme studies, suggests it could offer more effective management of DHT-related conditions. Additionally, its lower molecular weight hints at better potential for topical application, potentially offering advantages in treating conditions such as androgenic alopecia. Despite its potential, it has not advanced in development, possibly due to financial limitations, leaving its therapeutic prospects and side effect profile largely unexplored.
community 0.5mg Dutasteride promotes more “regrowth” than 5mg oral Minoxidil
Dutasteride promotes more hair regrowth than Minoxidil. Users discuss combining treatments for better results and share personal experiences with side effects.
community The theory that explains everything. The malloclusion theory has been proven.
Brian Dye's theory links skeletal malocclusion type II to hair loss, suggesting it's a blood flow issue. Treatments mentioned include minoxidil, finasteride, and anti-inflammatory drugs like benaxoprofen.
community Fats on your Head to Stop Hair Loss?
The conversation discusses the potential of long-chain unsaturated fatty acids, like oleic and linoleic acid, as an additional treatment for hair loss, which may inhibit the enzyme responsible for converting testosterone to DHT and promote hair growth. Users humorously suggest using oils topically and discuss other hair loss treatments, but the main focus is on the science behind fatty acids and their role in hair health.
community White Rice Lowers DHT and might cause post finasteride syndrome
White rice may lower DHT and potentially cause symptoms similar to post-finasteride syndrome. The user experienced muscle wasting, depression, and other symptoms after consuming large amounts of white rice.