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research Mechanical stress and the development of pseudo‐comedones and tunnels in Hidradenitis suppurativa/Acne inversa

29 citations , January 2016 in “Experimental Dermatology”

This article discusses how mechanical stress may contribute to the development of hidradenitis suppurativa lesions, drawing on historical research and highlighting the possible role of IL-17-mediated inflammation.

research Investigating material basis and molecular mechanism of Qing Cuo formula in the treatment of acne based on animal experiments, UPLC-LTQ-Orbitrap-MS and network pharmacology

4 citations , June 2023 in “Pharmaceutical Biology”

This study found that the Qing Cuo Formula significantly reduced serum androgen and inflammatory cytokine levels in hamsters with damp-heat acne and identified potential molecular mechanisms and active compounds involved.

research The Mechanism and Research Progress of Skin Microbiota in Pathogenesis of Acne

January 2025 in “Dermatology Research and Practice”

This study examines how skin microbiota and the gut-skin axis affect acne development, aiming to reveal mechanisms that could inform future treatment strategies for acne and other inflammatory skin conditions.

research Anti-EGFR mechanism of action: antitumor effect and underlying cause of adverse events.

91 citations , April 2006 in “PubMed”

This review summarizes adverse events associated with EGFR-targeting cancer therapies, such as skin rashes and lung disease, and reports no new clinical results.

research Formulation and clinical evaluation of niosomal methylene blue for successful treatment of acne

20 citations , April 2020 in “Journal of advanced Biomedical and Pharmaceutical Sciences”

This study investigated the use of methylene blue in a niosomal hydrogel for photodynamic treatment of acne and found that it led to significant improvement in inflammation compared to IPL treatment.

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community PP405 mechanism question - looking for discussion

7 upvotes 5 months ago

PP405 may promote short-term hair growth by pushing follicles into the growth phase, but concerns exist about long-term effects due to lack of rest phases. Users discuss various treatments like finasteride, minoxidil, spironolactone, alfatradiol, and investigational drugs like KX-826 and GT20029 for hair maintenance and regrowth.

community Ru58841 cleared my forehead acne

in Treatment 8 upvotes 1 year ago

RU58841 helped clear forehead acne. The user mixes it with 5% minoxidil and considers making a cream for acne treatment.

community is anyone using ru58841 against acne?

in Technology 3 upvotes 1 year ago

RU58841 is discussed as a potential treatment for acne and hair loss, with users debating its effectiveness and safety compared to other treatments like finasteride, minoxidil, and dutasteride. Concerns about RU58841's side effects and lack of clinical trials are raised, while some users share their personal experiences and routines involving RU58841 for hair loss.

community DHT Itch is real. The connection between Acne and Male Pattern Baldness shows this

in Research/Science 64 upvotes 3 years ago

The conversation discusses the link between seborrheic dermatitis, acne, and male pattern baldness, suggesting that DHT may cause both skin conditions and hair loss. Treatments mentioned include RU58841, finasteride, dutasteride, minoxidil, Nizoral shampoo, and other topical anti-androgens.

community Do you guys believe oral minoxidil causes faster aging of the face? (By mechanism like bloating, dark circles, and inhibition of collagen)

45 upvotes 1 year ago

Oral minoxidil may cause facial bloating and dark circles, making some users feel they look older. Some consider reducing the dosage or switching treatments due to these side effects.

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