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GlossaryAngiotensin-Converting Enzyme 2 (ACE2 receptor)

regulates blood pressure and is a SARS-CoV-2 entry point

Angiotensin-Converting Enzyme 2 (ACE2) is a protein found on the surface of many cell types, including those in the lungs, heart, and kidneys. It plays a crucial role in regulating blood pressure by converting angiotensin II, a molecule that can increase blood pressure, into angiotensin 1-7, which has the opposite effect. ACE2 is also known for being the entry point for the SARS-CoV-2 virus, which causes COVID-19, making it a significant focus of medical research.

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research Pathobiology Questions Raised by Telogen Effluvium and Trichodynia in COVID-19 Patients

18 citations, April 2021 in “Experimental Dermatology”

COVID-19 may cause hair loss and scalp pain due to inflammation and changes in hair follicle receptors, but these symptoms typically resolve in 2 to 4 months.

research The Probable Destructive Mechanisms Behind COVID-19 on Male Reproductive System and Fertility

17 citations, May 2021 in “Journal of Assisted Reproduction and Genetics”

COVID-19 may harm male fertility and damage the reproductive system.

research Comment on 'Androgens and Women: COVID-19 Outcomes in Women with Acne Vulgaris, Polycystic Ovarian Syndrome, and Hirsutism'

1 citations, April 2021 in “International Journal of Dermatology”

Women with conditions like PCOS may have a higher risk of COVID-19, but treatments like isotretinoin could help those with acne.

research Basic Mechanisms of SARS-CoV-2 Infection: Implications for Endocrine Systems

14 citations, July 2021 in “Reviews in endocrine and metabolic disorders”

SARS-CoV-2, the virus causing COVID-19, can affect all endocrine organs and systems, altering their function and potentially leading to disorders. Factors like diabetes and obesity increase infection risk and severity. Understanding these effects is key for effective treatment.

Immunological Aspects and Gender Bias During Respiratory Viral Infections Including Novel Coronavirus Disease-19 (COVID-19): A Scoping Review

research Immunological Aspects and Gender Bias During Respiratory Viral Infections Including Novel Coronavirus Disease-19 (COVID-19): A Scoping Review

11 citations, May 2021 in “Journal of Medical Virology”

Men are more likely to have severe respiratory viral infections like COVID-19 due to hormonal and genetic differences, while women generally have stronger immune responses.

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community Adrogens and Covid-19

in Treatment 8 upvotes 4 years ago

The possible increased risk of severe Covid-19 cases in men due to higher androgen levels, and how taking medications such as finasteride, dutasteride, spironolactone, enzalutamide, or canabidiol might help mitigate the severity of the disease.