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GlossaryAngiotensin-Converting Enzyme 2 (ACE2 receptor)

regulates blood pressure and is a SARS-CoV-2 entry point

Angiotensin-Converting Enzyme 2 (ACE2) is a protein found on the surface of many cell types, including those in the lungs, heart, and kidneys. It plays a crucial role in regulating blood pressure by converting angiotensin II, a molecule that can increase blood pressure, into angiotensin 1-7, which has the opposite effect. ACE2 is also known for being the entry point for the SARS-CoV-2 virus, which causes COVID-19, making it a significant focus of medical research.

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research Pathobiology Questions Raised by Telogen Effluvium and Trichodynia in COVID-19 Patients

18 citations , April 2021 in “Experimental Dermatology”

COVID-19 may cause hair loss and scalp pain due to inflammation and changes in hair follicle receptors, but these symptoms typically resolve in 2 to 4 months.

research The Probable Destructive Mechanisms Behind COVID-19 on Male Reproductive System and Fertility

17 citations , May 2021 in “Journal of Assisted Reproduction and Genetics”

COVID-19 may harm male fertility and damage the reproductive system.

research Comment on 'Androgens and Women: COVID-19 Outcomes in Women with Acne Vulgaris, Polycystic Ovarian Syndrome, and Hirsutism'

1 citations , April 2021 in “International Journal of Dermatology”

Women with conditions like PCOS may have a higher risk of COVID-19, but treatments like isotretinoin could help those with acne.

research Extrapulmonary Manifestations of Coronavirus Disease (COVID-19): Current Status - A Literature Review

2 citations , November 2022 in “Zaporozhye Medical Journal”

COVID-19 affects many body systems, causing a wide range of symptoms and complications.

research Insights Into Disparities Observed With COVID-19

147 citations , November 2020 in “Journal of Internal Medicine”

Age, health conditions, race, and gender affect COVID-19 risk.

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community Adrogens and Covid-19

in Treatment 7 upvotes 5 years ago

The possible increased risk of severe Covid-19 cases in men due to higher androgen levels, and how taking medications such as finasteride, dutasteride, spironolactone, enzalutamide, or canabidiol might help mitigate the severity of the disease.