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Research

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research Induction of basal cell carcinomas and trichoepitheliomas in mice overexpressing GLI-1

380 citations , March 2000 in “Proceedings of the National Academy of Sciences”

This study demonstrates that mice with ectopic expression of the human GLI-1 gene in their skin developed tumors resembling human basal cell carcinoma, suggesting that GLI-1 is central to tumor development without additional p53 or Ha ras mutations.

research Induction of basal cell carcinomas and trichoepitheliomas in mice overexpressing GLI-1

333 citations , March 2000 in “Proceedings of the National Academy of Sciences”

In this study, researchers established that increased expression of the human GLI-1 gene in mouse skin leads to the development of tumors that closely resemble human basal cell carcinomas, without requiring additional mutations in the p53 or Ha ras genes.

research Immunohistochemical localization of types 1 and 2 5α-reductase in human scalp

100 citations , September 1999 in “British Journal of Dermatology”

This study suggests that finasteride's effect on promoting hair growth in men with androgenetic alopecia may be due to its inhibition of 5aR2 localized in hair follicles.

research Insulin-like growth factor 1 and hair growth

98 citations , November 1999 in “Dermatology Online Journal”

This review discusses the effects of IGF-1 on hair follicle cell proliferation and differentiation, highlighting its roles in paracrine signaling, apoptosis prevention, and hair growth, but reports no new clinical results.

research Hyperandrogenism and Polycystic Ovary Syndrome in Women with Type 1 Diabetes Mellitus

96 citations , February 2007 in “The Journal of Clinical Endocrinology & Metabolism”

This review discusses the high prevalence of androgen excess and PCOS in women with type 1 diabetes but reports no new clinical findings; the authors highlight the underdiagnosis of hyperandrogenism in these patients.

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Community Join

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community Month 13 - Oral Fin, Top Min and Keto shampoo

in Is this regrowth? 10 upvotes 7 months ago

The user is using 1mg oral finasteride daily, applying topical minoxidil 1-2 times daily, and using Nizoral shampoo twice a week for hair regrowth. They are discussing their progress at month 13 of this treatment regimen.

community 13 Years on Fin, Losing Effectiveness, Started 0.5 Dut Once a Week, Getting Strange Nipple Sensitivity, Is This Something That Will Go Away? (Blood Test Results After 13 Years Included)

2 upvotes 1 year ago

After 13 years on finasteride, OP is experiencing reduced effectiveness and has started taking 0.5 mg of dutasteride weekly, noticing nipple sensitivity as a side effect. OP plans to increase the dutasteride dosage and retest hormone levels, while others suggest adjusting the dosage or trying different forms of dutasteride.

community (27M) 13 month update - fin and minoxidil

in Progress Pictures 683 upvotes 1 year ago

A 27-year-old male shared his 13-month progress using finasteride and topical minoxidil for hair regrowth, reporting significant improvement without noticeable side effects. He also mentioned losing 110 lbs, which may have contributed to his overall health and appearance.

community Over 13 months on 5% minoxidil and 6 months on finastride

in Progress Pictures 296 upvotes 1 year ago

A user stopped using 5% minoxidil and finasteride despite positive results to focus on enjoying life without the stress of hair care. They prioritize personal happiness and acceptance over hair maintenance.

community [M29] 13 months fin, 4 months topical min

5 upvotes 1 year ago

A 29-year-old male reports using 1.25mg finasteride daily and applying minoxidil twice daily to the temples for hair loss, noting modest progress over 13 months. He attributes rapid hair loss onset to creatine use and is considering a hair transplant in the future.

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Learn

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learn C 13-15 alkane

learn Butylene glycol

learn Scalp Micropigmentation

How do I choose the right hairline for scalp micropigmentation? Collaborate with your provider to design a hairline that suits your facial features.

learn Hair Transplant

Can women get hair transplants? Women can get hair transplants, and procedures are tailored to their specific hair loss patterns.
Is a hair transplant permanent? Transplanted hair is generally permanent but requires ongoing care to maintain results.
How many sessions will I need for a hair transplant? Providers give different answers, and the number is decided at consultation: some clinics quote courses of 3 to 6 sessions, but that pattern belongs to non-surgical treatments rather than to surgery. Ask your surgeon how many procedures your own case would need and how far apart they would be.
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