Search
for

    Glossary Spironolactone

    medication that blocks hormones to treat hair loss and acne

    Spironolactone, also known by the brand name Aldactone, is a medication primarily used as a diuretic and antihypertensive. It works by blocking the action of aldosterone, a hormone that regulates salt and water balance in the body. In addition to its primary uses, it is also prescribed off-label for conditions like acne and hirsutism (excessive hair growth) due to its anti-androgenic properties, and it can be beneficial in treating certain types of hair loss, such as androgenetic alopecia.

    Related Terms

    Learn 1 of 5

    1. Spironolactone Blood-pressure and diuretic drug with anti-androgen effects
    All learn results →

    Research 10 of 1000+

    1. Treatment of Hirsutism With Spironolactone JAMA · 1982 · 183 citations
    2. Comparison of flutamide and spironolactone in the treatment of hirsutism: a randomized controlled trial Fertility and Sterility · 1994 · 165 citations
    3. The effects of two doses of spironolactone on serum androgens and anagen hair in hirsute women Fertility and sterility · 1985 · 142 citations
    4. A Novel Use of Spironolactone: Treatment of Hirsutism 1980 · 124 citations
    5. Oral Spironolactone for Acne Vulgaris in Adult Females: A Hybrid Systematic Review American Journal of Clinical Dermatology · 2017 · 117 citations
    6. Spironolactone versus placebo or in combination with steroids for hirsutism and/or acne Cochrane library · 2009 · 112 citations
    7. Oral spironolactone therapy for female patients with acne, hirsutism or androgenic alopecia British Journal of Dermatology · 1985 · 101 citations
    8. Comparison of Spironolactone, Flutamide, and Finasteride Efficacy in the Treatment of Hirsutism: A Randomized, Double Blind, Placebo-Controlled Trial1 The Journal of Clinical Endocrinology and Metabolism · 2000 · 94 citations
    9. Follicular delivery of spironolactone via nanostructured lipid carriers for management of alopecia International Journal of Nanomedicine · 2014 · 89 citations
    10. Female pattern hair loss: a pilot study investigating combination therapy with low-dose oral minoxidil and spironolactone International Journal of Dermatology · 2017 · 80 citations
    All research results →

    Community 10 of 255

    1. Doctor prescribed me Spironolactone instead of Finasteride Reddit · 15 Sept 2026
    2. If i add a little daily dose of spironolactone (25 mg a day) would the improvement to my hair loss be significant? and also how likely is it to give me unwanted effects? My current regimen is 6 days / week oral Finasteride, 1 day / week oral Dutasteride and twice a day minoxidil foam Reddit · 29 Aug 2026
    3. Any men here taking oral spironolactone? Reddit · 16 Jul 2026
    4. I am a 30 yo woman and having been taking oral minoxidil and spirinolactone... nothing. What gives? Reddit · 24 Apr 2026
    5. Why is nobody talking about topical Spironolactone? Reddit · 10 Apr 2026
    6. Dose of oral spironolactone for males to stop hairloss when 5ari blockers not working, any idea Reddit · 5 Apr 2026
    7. spironolactone vs dutasteride Which one is more effective? Reddit · 24 Mar 2026
    8. What combination should I do of min, fin and spironolactone - woman Reddit · 16 Jan 2026
    9. Are there any males here that use (or have used) topical spironolactone? Reddit · 2 Jan 2026
    10. Any male on topical spironolactone? Reddit · 20 Dec 2025
    All community results →