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Glossary Dutasteride

medication that inhibits DHT to treat enlarged prostate and hair loss

Dutasteride, also known by the brand name Avodart, is a medication primarily used to treat benign prostatic hyperplasia (BPH), which is an enlarged prostate. It works by inhibiting the action of the enzyme 5-alpha-reductase, which converts testosterone to dihydrotestosterone (DHT), a hormone that contributes to prostate growth. Additionally, dutasteride is sometimes used off-label to treat male pattern baldness due to its ability to reduce DHT levels, which are implicated in hair loss.

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learn Dutasteride

5-alpha reductase inhibitor that blocks both enzyme types, a stronger DHT blocker than finasteride

Can I use dutasteride without a prescription? All about its sale and regulations. Dutasteride requires a prescription and cannot be used without medical supervision.
Will I notice changes in my body if I start taking dutasteride? Dutasteride lowers DHT, so labels and trials describe prostate shrinkage over 3-6 months and, off-label, slowed hair loss; the same sources list sexual side effects that may persist after stopping, breast and semen changes, rare allergic reactions, and an observational link to depression.
Dutasteride: What if I just want to grow back some hair without taking pills every day? There is no approved topical dutasteride; it exists only as pharmacy-compounded preparations and small studies, so its effectiveness and long-term safety are not established.
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learn Finasteride

Popular 5-alpha reductase inhibitor that lowers DHT, taken as a pill or used topically

learn tamsulosin

learn Fluridil

Topical anti-androgen sold as a cosmetic lotion

learn Bicalutamide

Nonsteroidal anti-androgen, originally a prostate cancer drug

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Research

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research Marked Suppression of Dihydrotestosterone in Men with Benign Prostatic Hyperplasia by Dutasteride, a Dual 5α-Reductase Inhibitor

408 citations , May 2004 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism”

This study found that dutasteride more effectively reduced serum dihydrotestosterone levels than finasteride in patients with benign prostatic hyperplasia.

research The importance of dual 5α-reductase inhibition in the treatment of male pattern hair loss: Results of a randomized placebo-controlled study of dutasteride versus finasteride

215 citations , November 2006 in “Journal of The American Academy of Dermatology”

This study found that dutasteride increased scalp hair growth in men with male pattern hair loss, particularly at a 2.5 mg dose, and was more effective than finasteride over 24 weeks.

research The Effect of 5α-Reductase Inhibition with Dutasteride and Finasteride on Semen Parameters and Serum Hormones in Healthy Men

195 citations , February 2007 in “The Journal of Clinical Endocrinology and Metabolism”

In this study, administering 5alpha-reductase inhibitors reduced dihydrotestosterone levels and was associated with mild, reversible decreases in semen parameters in healthy men.

research A randomized, active- and placebo-controlled study of the efficacy and safety of different doses of dutasteride versus placebo and finasteride in the treatment of male subjects with androgenetic alopecia

97 citations , January 2014 in “Journal of The American Academy of Dermatology”

This study found that dutasteride increased hair growth and restoration in men with androgenetic alopecia more effectively than finasteride and was well tolerated over 24 weeks.

research Efficacy, safety, and tolerability of dutasteride 0.5 mg once daily in male patients with male pattern hair loss: A randomized, double-blind, placebo-controlled, phase III study

92 citations , June 2010 in “Journal of The American Academy of Dermatology”

This study found that 0.5 mg of dutasteride significantly improved hair growth compared to placebo and was well tolerated over six months in men with male pattern hair loss.

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Community Join

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community Dutasteride - Eyebrow Thinning

40 upvotes 4 days ago

Dutasteride may cause eyebrow thinning, with some users considering minoxidil to counteract this effect. Users report varying experiences with hair regrowth and side effects from treatments like minoxidil and finasteride.

community Dutasteride 2.5mg and oral min 5mg

10 upvotes 4 days ago

The conversation is about using Dutasteride 2.5mg and Minoxidil 5mg to address hair thinning and receding after two years on finasteride. Another user shares their regimen, including Ketoconazole, Dutasteride, Finasteride, Oral Minoxidil, topical treatments, and microneedling, attributing hair loss to stress and poor sleep.

community dutasteride feels like a commitment for life

15 upvotes 5 days ago

The conversation discusses the commitment of using treatments like finasteride and dutasteride for hair loss, comparing it to daily routines like brushing teeth. Users express that while these treatments are not a lifetime commitment, they are necessary for maintaining hair, similar to other cosmetic or hygiene practices.

community Dutasteride 4 months shedding.

4 upvotes 5 days ago

After 4 months of improvement on dutasteride, the user experienced heavy hair shedding and is curious about others' experiences with similar shedding cycles. The conversation focuses on hair regrowth cycles and the effects of dutasteride.

community dutasteride 0.5 and oral minoxidil 2.5 progress pictures

37 upvotes 5 days ago

The user experienced thicker and darker hair at the temples after 4 months of using oral minoxidil and dutasteride, with an intense shedding phase between 1 to 3 months. They report no side effects and positive regrowth, with others noting dutasteride's effectiveness over finasteride.

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