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research 9-cis-Retinoic Acid Capsules in the Treatment of AIDS-Related Kaposi Sarcoma

52 citations , February 2003 in “Archives of dermatology”

In this open-label trial, 9-cis-retinoic acid showed moderate activity against Kaposi sarcoma in AIDS patients, but its use is limited by substantial side effects at higher doses.

research Retinoid-mediated stimulation of steroid sulfatase activity in myeloid leukemic cell lines requires RARα and RXR and involves the phosphoinositide 3-kinase and ERK-MAP kinase pathways

24 citations , September 2005 in “Journal of Cellular Biochemistry”

This study found that all-trans and 9-cis retinoic acids increase steroid sulfatase activity in HL60 cells through mechanisms involving RARα/RXR heterodimers and multiple signaling pathways.

research Retinoids Modulate MITF: A Novel Mechanism in the Regulation of Melanogenesis

January 2015

This study identified 92 novel regulators of melanogenesis, highlighting Aldehyde dehydrogenase 1A1 as a potential target for developing new treatments for hyperpigmentation disorders like melasma.

research Retinoids Modulate MITF: A Novel Mechanism in the Regulation of Melanogenesis - eScholarship

January 2015

This study identified ALDH1A1 as a regulator of melanogenesis and suggests its inhibition, through agents like cyanamide, may be a promising therapeutic approach for treating hyperpigmentation disorders such as melasma.

research Protein Kinase Cε, Which Is Linked to Ultraviolet Radiation-Induced Development of Squamous Cell Carcinomas, Stimulates Rapid Turnover of Adult Hair Follicle Stem Cells

10 citations , January 2013 in “Journal of skin cancer”

In this study, PKC ε transgenic mice exposed to ultraviolet radiation showed increased hair follicle stem cell frequency and altered gene expression compared to wild-type mice, suggesting a potential role in skin cancer susceptibility.

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community 9 months of minoxidil , finasteride, spironolactone, estradiol

61 upvotes 2 years ago

User shared progress pictures after 9 months of using minoxidil, finasteride, spironolactone, and estradiol for hair loss. Significant regrowth was noted, especially after starting estradiol.

community Progress: 1 year mtf hrt, 9 months Min/Fin

in Transgender 118 upvotes 1 year ago

The user experienced significant hair regrowth after one year on male-to-female hormone replacement therapy (HRT) and nine months using minoxidil and finasteride. They noted a reduction in body hair and attributed much of the hair regrowth to the addition of minoxidil.

community Well… I Did It. Estrogen Saved My Hairline

in Transgender 732 upvotes 2 years ago

OP transitioned and used Spironolactone, Estradiol Valerate, Minoxidil, and dermarolling, resulting in significant hair regrowth. They advise this method may not be suitable for cis men.

community 200 days on dut + min, what do you think?

599 upvotes 11 months ago

The user reports significant hair regrowth after 200 days using dutasteride and minoxidil, attributing changes to hair dye. Others doubt the authenticity and discuss treatment effectiveness and side effects.

community Guaranteed Way to Revive ALL Follicles. Transition, and then Transition Back & Maintain (for Men)

250 upvotes 1 year ago

Transitioning genders humorously suggested for hair regrowth, noting some transgender individuals experience this. Discusses treatments like minoxidil, finasteride, and hormone therapy, but advises against transitioning solely for hair regrowth.

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