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    Did you mean 5-alpha reductase inhibitor?
    Glossary5α-reductase inhibition (5-alpha reductase inhibitor)

    blocking enzyme that converts testosterone to hair-loss hormone DHT

    5α-reductase inhibition refers to the process of blocking the enzyme 5α-reductase, which is responsible for converting testosterone into dihydrotestosterone (DHT). DHT is a hormone that can contribute to hair loss and conditions like benign prostatic hyperplasia. By inhibiting this enzyme, medications like finasteride and dutasteride can help reduce hair loss and treat these conditions.

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      Frontline, gold standard treatment for combatting androgenic alopecia

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      a natural and far less effective alternative to Finasteride

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      acid used for antimicrobial, anti-inflammatory and anti-androgenic properties

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      herb and oil with stimulant, circulatory, anti-inflammatory and antioxidant properties

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      community Do these two supplements inhibit 5alpha-reductase?

      in Chat  1 upvotes 4 years ago
      Pumpkin Seed Oil and Perilla Oil (with alpha-lipoic acid, linoleic acid, and oleic acid) are discussed as potential 5alpha-reductase inhibitors. The conversation focuses on their effectiveness for hair loss treatment.
      FCE 28260: A Forgotten 5α-Reductase Inhibitor

      community FCE 28260: A Forgotten 5α-Reductase Inhibitor

      in Research  330 upvotes 3 months ago
      FCE 28260 (PNU 156765), an under-explored 5α-reductase inhibitor, showcases promising results in research by Giudici et al., outperforming well-known treatments like Finasteride in reducing the conversion of testosterone to DHT. Its superior efficacy, demonstrated through lower IC50 values in both natural and human recombinant enzyme studies, suggests it could offer more effective management of DHT-related conditions. Additionally, its lower molecular weight hints at better potential for topical application, potentially offering advantages in treating conditions such as androgenic alopecia. Despite its potential, it has not advanced in development, possibly due to financial limitations, leaving its therapeutic prospects and side effect profile largely unexplored.