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research Epigallocatechin Gallate-Mediated Alteration of the MicroRNA Expression Profile in 5α-Dihydrotestosterone-Treated Human Dermal Papilla Cells

16 citations , January 2016 in “Annals of Dermatology”

This study suggests that epigallocatechin gallate (EGCG) from green tea may counteract DHT-induced hair follicle damage by modifying the miRNA expression profile in human dermal papilla cells.

research Endocrine treatment of benign prostatichypertrophy: Current concepts

11 citations , January 1991 in “Urology”

This article reviews the potential of combining antiandrogenic and antiestrogenic treatments for BPH, highlighting aromatase inhibitors, but presents no new clinical results; further research is needed.

research Recent Advances in Drug Design and Drug Discovery for Androgen- Dependent Diseases

11 citations , February 2016 in “Current Medicinal Chemistry”

This review discusses various targets for treating prostate cancer and benign prostatic hyperplasia and reports on recent studies of new compounds and 5α-reductase inhibitors, but provides no new experimental results.

research Inhibitory activities of some traditional Chinese herbs against testosterone 5α-reductase and effects of Cacumen platycladi on hair re-growth in testosterone-treated mice

25 citations , November 2015 in “Journal of Ethnopharmacology”

This study found that Cacumen platycladi extract significantly promoted hair growth and reduced dihydrotestosterone levels by inhibiting 5α-reductase activity in an androgen-sensitive mouse model.

research L‐Carnitine–L‐tartrate promotes human hair growth in vitro

26 citations , October 2007 in “Experimental Dermatology”

This study found that l-carnitine stimulated hair growth in vitro by promoting proliferation and reducing apoptosis in human scalp hair follicles, suggesting potential as a treatment for hair loss.

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Community Join

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community Head and Shoulders 2-in-1 shampoo and conditioner use resulting in hair growth by reducing scalp inflammation and DHT?

8 upvotes 2 years ago

User experienced new hair growth after using Head and Shoulders 2-in-1 shampoo/conditioner, attributing it to pyrithione zinc reducing scalp inflammation and DHT. They seek others' experiences with anti-dandruff products.

community Can Zinc Affect Finasteride Efficacy?

6 upvotes 3 years ago

A 20-year-old male is concerned that zinc might reduce the effectiveness of finasteride for hair loss, as zinc is known to increase DHT levels. Users suggest that zinc, at certain doses, has anti-androgenic properties and is unlikely to negatively impact finasteride's efficacy.

community RU58841 or topical spironolactone??

4 upvotes 4 years ago

The conversation is about choosing between RU58841 and topical spironolactone for hair loss treatment. The user is currently using a topical solution with minoxidil, alfatradiol, and progesterone, and is concerned about side effects and effectiveness of both RU58841 and spironolactone.

community Dut kept my hair but nuked my peepee

in Finasteride/Dutasteride 101 upvotes 9 months ago

A user experienced hair retention but sexual side effects after using dutasteride for a year. Others shared similar experiences with finasteride and dutasteride, suggesting consulting a doctor for persistent issues.

community Why do people here trust Kevin Mann?

36 upvotes 6 years ago

Concerns about finasteride's side effects on neurosteroids and brain health, with skepticism towards Kevin Mann's advice. Users discuss using finasteride, minoxidil, and RU58841 for hair loss, with mixed opinions on their safety and effectiveness.

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