December 2025 in “Molecular Pain” This study identified that the MC-5-HT-HTR2A axis plays a role in chronic pruritus in a mouse model of SADBE-induced allergic contact dermatitis, suggesting potential for therapeutic targeting.
18 citations
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September 1972 in “British Journal of Pharmacology” In this study on male rats, parachlorophenylalanine treatment induced hypersexual behavior and hair loss linked to increased social interaction but had no effect on brain serotonin when testosterone was used instead.
December 2012 in “Bulletin of Egyptian Society for Physiological Sciences” This study found that topical application of copper (II) albumin complex improved healing signs in rats with full thickness thermal burns, enhancing antioxidant, anti-inflammatory, and pain modulating effects.
9 citations
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March 2024 in “Journal of Biomaterials Applications” This study developed dissolving microneedles using specific polymers for transdermal delivery of rizatriptan benzoate, demonstrating improved drug skin penetration and significant alleviation of migraine symptoms in vivo compared to passive diffusion, suggesting potential advantages over conventional treatment methods for acute migraine.
78 citations
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March 2004 in “Annals of Oncology” This study found that the combination of docetaxel, cisplatin, and 5-fluorouracil is active and feasible for treating squamous cell carcinoma of the head and neck, with dose level I recommended for further testing.