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Did you mean 5-alpha-reductase inhibitor?

Glossary 5-alpha-reductase inhibitor

blocks enzyme converting testosterone to dihydrotestosterone (DHT)

A 5-alpha-reductase inhibitor is a type of medication that blocks the enzyme 5-alpha-reductase, which is responsible for converting testosterone into dihydrotestosterone (DHT). By reducing DHT levels, these inhibitors can help treat conditions like male pattern baldness and benign prostatic hyperplasia (BPH).

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Research

5 / 1000+ results

research Influencia del tratamiento con alfa bloqueantes e inhibidores de la 5 alfa reductasa en los hallazgos morfológicos e inmunohistoquímicos de la hiperplasia benigna de próstata

January 2002 in “Dialnet (Universidad de la Rioja)”

This study found that the epithelial changes in benign prostatic hyperplasia treated with finasteride resembled the pattern of healthy prostates.

What Do We Know About 5-Alpha Reductase Inhibitors?

research O que sabemos sobre os inibidores da 5 alfa redutase?

January 2018 in “Surgical and Cosmetic Dermatology”

This review provides an in-depth examination of the efficacy and safety of finasteride and dutasteride, commonly used for treating benign prostatic hyperplasia and male androgenetic alopecia.

research SÍNDROME PÓS-FINASTERIDA E O IMPACTO DOS INIBIDORES DA 5-ALFA REDUTASE NOS EIXOS NEUROENDÓCRINO E METABÓLICO

May 2026 in “RECIMA21 - Revista Científica Multidisciplinar - ISSN 2675-6218”

This study reviewed recent scientific evidence on the neuroendocrine and metabolic impacts of chronic use of 5-alpha reductase inhibitors, detailing its association with sexual dysfunction, mood disorders, insulin resistance, and other metabolic disorders, suggesting persistent biopsycho-social risks beyond transient side effects in users.

Female Pattern Hair Loss: A Review Article

research Female Pattern Hair Loss

57 citations , October 2013 in “international journal of endocrinology and metabolism”

This review discusses clinical features, differential diagnosis, and treatments for female pattern hair loss, emphasizing the use of 2% topical Minoxidil and exploring alternative off-label therapies.

research Frontal Fibrosing Alopecia: An Update on Epidemiology and Treatment

7 citations , October 2015 in “Actas Dermo-Sifiliográficas”

This article reviews the increasing incidence of frontal fibrosing alopecia since its first description in 1994 and reports no new results.

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Community Join

5 / 1000+ results

community 9 months on topical finasteride (0.05%) + 5% minoxidil.

in Progress Pictures 26 upvotes 2 months ago

The conversation discusses a user's 9-month progress using topical finasteride (0.05%) and minoxidil (5%) with microneedling for hair loss, noting some improvement without side effects. Suggestions include trying oral treatments or switching to topical dutasteride for potentially better results.

community Did Dutasteride change how you look physically? your facial profile such as skin thickness, fat distribution or softness?

in Finasteride/Dutasteride 51 upvotes 1 year ago

Dutasteride and finasteride can cause changes in physical appearance, like more feminine features and increased water retention. Users report side effects such as reduced libido, weight gain, and improved skin clarity, while some notice no significant changes.

community Has anyone ever tried using (all topicals) finasteride + minoxidil + rosemary oil + castor oil + stemoxydine all over the course of a few months/years?

4 upvotes 2 years ago

The user is using topical finasteride and minoxidil for hair loss and is considering adding rosemary oil, castor oil, and stemoxydine to their routine. They are asking if anyone has experience with this combination or a similar one.

community (27M) Seems like first PRP session just worsen my hair...

7 months ago

A user experienced worsened hair condition after a PRP session and is considering stopping further sessions. They are using a Dermapen, electric massage, iron, saw palmetto, and plan to start minoxidil, but have had side effects with finasteride and are advised to consider dutasteride under medical supervision.

community I interviewed Kintor: GT20029 Clinical Trial Pictures. As well as KX826.

156 upvotes 1 year ago

GT20029 and KX826 are promising hair loss treatments, with GT20029 increasing hair count and KX826 showing significant results. KX826 may be a good alternative for those who can't use finasteride or dutasteride, though results vary.

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