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    Research 10 of 1000+

    1. The 5 Alpha-Reductase Isozyme Family: A Review of Basic Biology and Their Role in Human Diseases Advances in Urology · 2011 · 218 citations
    2. The biochemical and phenotypic characterization of females homozygous for 5 alpha-reductase-2 deficiency. The Journal of Clinical Endocrinology & Metabolism · 1995 · 54 citations
    3. 5 alpha-reductase-2 gene mutations in the Dominican Republic. The Journal of Clinical Endocrinology & Metabolism · 1996 · 53 citations
    4. Reduced levels of 5-α reductase 2 in adult prostate tissue and implications for BPH therapy 2011 · 39 citations
    5. 5-Alpha reductase deficiency Current Opinion in Endocrinology, Diabetes and Obesity · 2014 · 38 citations
    6. Steroid 5α-reductase 2 deficiency leads to reduced dominance-related and impulse-control behaviors Psychoneuroendocrinology · 2018 · 14 citations
    7. Docking and Molecular Dynamics Identify Leads against 5 Alpha Reductase 2 for Benign Prostate Hyperplasia Treatment Journal of Chemistry · 2023 · 10 citations
    8. Synthesis and activity of 8-substituted benzo[c]quinolizin-3-ones as dual inhibitors of human 5α-reductases 1 and 2 Bioorganic & Medicinal Chemistry Letters · 2004 · 9 citations
    9. Homology Modeling of 5-alpha-Reductase 2 Using Available Experimental Data Interdisciplinary sciences: computational life sciences · 2018 · 5 citations
    10. Extract of <i>Plumbago zeylanica</i> enhances the growth of hair follicle dermal papilla cells with down‐regulation of 5α‐reductase type II Journal of Cosmetic Dermatology · 2020 · 4 citations
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    Community 10 of 1000+

    1. 5 alpha reductase type 1 is in brain tissue producing the main endogenous gabaergic allopregnanolone, not 2. How can finasteride as a 5ar2 lower that? Reddit · 3 Oct 2024
    2. Which Saw Palmetto is good for blocking 5 alpha reductase, Serenoa repens or Chamaerops humilis? Reddit · 26 Jun 2020
    3. Does caffeine inhibit 5-α-reductase? Reddit · 27 Dec 2019
    4. Does anyone know about the mechanism between creatine and 5-alpha reductase? Reddit · 25 Mar 2019
    5. FCE 28260: A Forgotten 5α-Reductase Inhibitor Community · 22 Aug 2024
    6. Androsterone as a Neurosteroid Replacement Strategy for 5α-Reductase Inhibitor–Associated Sexual and Affective Dysfunction Reddit · 15 Jul 2026
    7. Did anybody use beta sisterol for hair loss? I saw in many articles in the internet that said that beta sisterol blocks dht by inhibiting 5a reductase type 2 enzyme and some reviews of people who said that it worked better than saw palmetto in terms of stoping hair loss and helping prostate. Reddit · 11 May 2023
    8. I've been afraid to start Finasteride treatment for 5 years, on it for 2 weeks, regret that hadn't started it earlier and here's my story Reddit · 28 Sept 2021
    9. Approximation of Scalp DHT Suppression Between 0.05 mg to 2.5 mg Reddit · 28 Jan 2024
    10. Head and Shoulders 2-in-1 shampoo and conditioner use resulting in hair growth by reducing scalp inflammation and DHT? Reddit · 27 Jun 2024
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    Learn 6 of 24

    1. Dutasteride 5-alpha reductase inhibitor that blocks both enzyme types, a stronger DHT blocker than finasteride
    2. Finasteride Popular 5-alpha reductase inhibitor that lowers DHT, taken as a pill or used topically
    3. Saw Palmetto Palm-berry extract taken as a supplement
    4. Azelaic Acid Acid used in acne and rosacea creams
    5. Rosemary Herb whose oil is used in hair care
    6. Neem Oil Oil from the neem tree, used in traditional remedies
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