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    GlossarySteroid 5 Alpha-Reductase 1

    converts testosterone into a more potent androgen, dihydrotestosterone

    Steroid 5 Alpha-Reductase 1 (SRD5A1) is an enzyme that converts testosterone into dihydrotestosterone (DHT), a more potent androgen hormone. This enzyme plays a significant role in the development of male characteristics and is also implicated in conditions like androgenic alopecia (male pattern baldness) and benign prostatic hyperplasia.

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      learn Finasteride

      Frontline, gold standard treatment for combatting androgenic alopecia

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      a natural and far less effective alternative to Finasteride

      learn Azelaic Acid

      acid used for antimicrobial, anti-inflammatory and anti-androgenic properties

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      herb and oil with stimulant, circulatory, anti-inflammatory and antioxidant properties

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      community We need actual hair loss studies on Epristeride

      in Research/Science  6 upvotes 1 month ago
      Epristeride is a selective 5 alpha reductase type 2 inhibitor that may reduce scalp DHT similarly to finasteride, with potentially fewer side effects. It is suggested that combining epristeride with finasteride or dutasteride could enhance hair loss treatment effectiveness.

      community Trying to understand finasteride side effects and post finasteride syndrome

      in Finasteride/Dutasteride  73 upvotes 4 years ago
      The conversation discusses the side effects of finasteride, including low libido and erectile dysfunction, and the possibility of these effects being permanent, known as post-finasteride syndrome (PFS). Some users report personal experiences with PFS and debate whether the condition is real, with varying opinions on the reversibility of side effects and the role of individual biology.

      community 5ARI (dutasteride) Associated with Adverse Metabolic Effects

       23 upvotes 6 years ago
      Dutasteride is associated with increased blood glucose, HbA1c, LDL cholesterol, and liver enzyme activity, potentially leading to diabetes, NAFLD, and liver metabolism changes. The conversation highlights concerns about these adverse effects and calls for more studies, including on finasteride.