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This study developed 3DEEP, a tissue clearing and spatial transcriptomic method, to map hair follicle development in a single time point from a 12-hour-old mouse, detailing molecular stages, signaling dynamics, and structural changes within developing follicles.

This study provided a dynamic 4D atlas showing the development process of mouse hair follicles through a telescope-like model, revealing new insights into the origin of hair follicle stem cells.

This article reviews the steps and methods involved in preparing skin tissues for three-dimensional volumetric imaging, highlighting its potential to provide detailed insights into skin structure not possible with traditional 2D histology, but reports no new findings.

This study used a 3D simulation to show that human hair provides varying levels of UV protection depending on head orientation and hair alignment, highlighting hair's role in scalp UV protection, especially for those with alopecia.

This review found that 3D bioprinting significantly advances skin tissue engineering by enabling the creation of complex, patient-specific skin structures, though technological and regulatory challenges persist, particularly in areas like scalability and physiological mimicry.