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18-β-Glycyrrhetinic Acid Promotes Hair Growth by Stimulating the Proliferation of Dermal Papilla Cells and Outer Root Sheath Cells, and Extends the Anagen Phase by Inhibiting 5α-Reductase

research 18-β-Glycyrrhetinic Acid Promotes Hair Growth by Stimulating the Proliferation of Dermal Papilla Cells and Outer Root Sheath Cells, and Extends the Anagen Phase by Inhibiting 5α-Reductase

July 2024 in “Biological and Pharmaceutical Bulletin”

Licorice extract helps hair growth and may treat hair loss.

research Testicular Steroidogenesis: Production and Regulation of Testosterone and Dihydrotestosterone

5 citations, January 2017 in “Endocrinology”

Genetic defects in testosterone production can cause hormonal and developmental disorders, and more research is needed to understand androgen regulation and develop safer treatments.

Non-Classic Congenital Adrenal Hyperplasia Due to 21-Hydroxylase Deficiency Revisited: An Update with a Special Focus on Adolescent and Adult Women

research Non-Classic Congenital Adrenal Hyperplasia Due to 21-Hydroxylase Deficiency Revisited: An Update with a Special Focus on Adolescent and Adult Women

117 citations, May 2017 in “Human Reproduction Update”

The update highlights that non-classic congenital adrenal hyperplasia is common in women with excess male hormones, requires specific hormone tests for diagnosis, and has various treatment options depending on age and symptoms.

11α-Hydroxyprogesterone, a Potent 11β-Hydroxysteroid Dehydrogenase Inhibitor, Is Metabolized by Steroid-5α-Reductase and Cytochrome P450 17α-Hydroxylase/17,20-Lyase to Produce C11α-Derivatives of 21-Deoxycortisol and 11-Hydroxyandrostenedione In Vitro

research 11α-Hydroxyprogesterone, a Potent 11β-Hydroxysteroid Dehydrogenase Inhibitor, Is Metabolized by Steroid-5α-Reductase and Cytochrome P450 17α-Hydroxylase/17,20-Lyase to Produce C11α-Derivatives of 21-Deoxycortisol and 11-Hydroxyandrostenedione In Vitro

7 citations, April 2019 in “The Journal of Steroid Biochemistry and Molecular Biology”

11α-Hydroxyprogesterone is changed into different substances by certain enzymes and may play a role in prostate cancer.

research TSPO Activation Modulates the Effects of High Pressure in a Rat Ex Vivo Glaucoma Model

16 citations, September 2016 in “Neuropharmacology”

Activating TSPO helps protect the retina from damage caused by high eye pressure in glaucoma.

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Community Join

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community The theory that explains everything - First Evidence of Hair regrow attributed to upregulating 3aHSD

in Treatment 173 upvotes 3 years ago

Hair regrowth treatment involving 3aHSD enzyme shows 6% improvement in 18 weeks. Sulforaphane, L-Menthol, and Dexpanthenol are potential ingredients for new hair loss solution.

community The theory that explains everything. Community Crowdfund

in Chat 104 upvotes 3 years ago

3aHSD enzyme's role in hair loss and a crowdfund for research. Goal: explore new treatments, study RU58841, and develop natural topical product.

community What became of this PROMISING theory?

in Research/Science 9 upvotes 4 months ago

The conversation discusses skepticism and mixed opinions about a hair loss theory, mentioning treatments like Minoxidil, finasteride, RU58841, and Procyanidin B2. There is criticism of a content creator named HairCafe and the difficulty in obtaining effective sulforaphane supplements.

community As a follow up on u/joaopassos4444 's amazing post, short video of Sulforaphane supplements vs. broccoli sprouting. 2 brands are mentioned with the optimal dosage. Thought it would help!

in Research/Science 20 upvotes 3 years ago

The conversation discusses hair loss treatments, specifically Minoxidil, finasteride, RU58841, and Sulforaphane supplements. Two brands of Sulforaphane supplements, Avmacol and Prostaphane, are mentioned with optimal dosages.

community 3α-Hydroxysteroid dehydrogenase community driven study, not anytime soon guys.

in Research/Science 102 upvotes 3 years ago

High cost of studying 3α-Hydroxysteroid dehydrogenase in hair loss led to suggestions of crowdfunding for research. Users discussed using Procyanidin B2/melatonin topical treatment and tracking funds with blockchain.

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