9 citations
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March 2022 in “Journal of the Endocrine Society” This study found that testosterone more accurately predicts PCOS diagnosis than 11-oxyandrogens, which were linked with hirsutism severity and showed varying responses to contraceptive and metformin treatments.
May 2021 in “Journal of the Endocrine Society” This study found that while 11-oxyandrogens do not aid in diagnosing PCOS, they correlate with hirsutism severity, and 11-ketotestosterone levels decrease with combined oral contraceptive therapy.
15 citations
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July 2019 in “Lasers in surgery and medicine” This study found that 1,540 nm fractional erbium-glass laser treatment combined with topical minoxidil significantly increased hair regrowth in alopecia areata patches compared to minoxidil alone, with response rates of 60% versus 16%, though the long-term effects remain unknown.
34 citations
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November 2010 in “Development” In this study, epidermal Notch activation increased jagged 1 expression, leading to skin changes like thickening and blistering, with these effects inhibited when jagged 1 was absent.
32 citations
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August 2015 in “Journal of Investigative Dermatology” In this study using a mouse model, Prom1+ dermal papilla cells were found to regulate the size of the papilla via β-catenin communication but did not aid in dermal repair.