Does Zinc Have a Role in Alopecia Areata? A Clinic-Biochemical Study

February 2023 in “ Global journal of health sciences and research ”

Gowtham Saravanan, Karthikeyan Kaliyaperumal

alopecia areata serum zinc levels Severity of Alopecia Tool score zinc deficiency patchy hair loss calorimetrically zinc

From the encyclopedia

Alopecia Areata →

autoimmune disorder causing patchy hair loss

Zinc →

Studysummary This study found no association between serum zinc levels and alopecia areata severity in patients.

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Research cited in this study

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research Evaluation of Serum Zinc Level in Patients With Newly Diagnosed and Resistant Alopecia Areata

52 citations , July 2015 in “International Journal of Dermatology”

This study found that patients with alopecia areata had significantly lower serum zinc levels, which correlated inversely with disease severity, duration, and resistance to therapies, suggesting zinc assessment as a marker of disease status.

research Epidemiology and Burden of Alopecia Areata: A Systematic Review

144 citations , July 2015 in “Clinical, Cosmetic and Investigational Dermatology”

This review reports that alopecia areata affects about 2% of people globally and is linked with psychiatric and medical comorbidities, highlighting its significant disease burden.

research Comparison of Zinc, Copper, and Iron Content in Hair and Serum in Alopecia Areata Patients with Normal Group

21 citations , January 2014 in “Dermatology Research and Practice”

This study found no significant difference in serum and hair levels of iron, zinc, and copper between female alopecia areata patients and healthy controls.

research Some Trace Elements' Level in Alopecia Areata

9 citations , January 2013

This study found that serum levels of zinc, copper, and selenium were significantly lower in patients with alopecia areata compared to healthy controls, regardless of the number of hair loss patches.

research Alopecia Areata: An Update

67 citations , January 2013 in “Indian Journal of Dermatology, Venereology and Leprology”

This review discusses the causes, associated conditions, and treatment options for alopecia areata, such as corticosteroids and wigs, but reports no new clinical findings.

research Analysis of Serum Zinc and Copper Concentrations in Hair Loss

73 citations , January 2013 in “Annals of Dermatology”

This study observed that patients with various types of hair loss had significantly lower serum zinc levels compared to healthy controls, suggesting zinc disturbance may play a role in the condition.

The Therapeutic Effect and Changed Serum Zinc Level After Zinc Supplementation in Alopecia Areata Patients with Low Serum Zinc Level

research The Therapeutic Effect and Changed Serum Zinc Level After Zinc Supplementation in Alopecia Areata Patients with Low Serum Zinc Level

65 citations , January 2009 in “Annals of Dermatology”

In this study, oral zinc supplementation for twelve weeks increased serum zinc levels in alopecia areata patients with low zinc, showing positive hair regrowth in 66.7% of participants, though this was not statistically significant.

research The Pattern and Profile of Alopecia Areata in Singapore: A Study of 219 Asians

275 citations , November 2002 in “International Journal of Dermatology”

This study found that among an Asian population with alopecia areata, commonly first episodes occurred before age 40, with severe cases linked to psychological effects and treatments showing significant regrowth.

research Element Concentrations in Serum, Erythrocytes, Hair, and Urine of Alopecia Patients

51 citations , March 1986 in “Acta Dermato Venereologica”

This study found no differences in trace element concentrations between Finnish alopecia patients and the normal population, but noted significant serum copper variation among different alopecia subtypes.