Comparison of Young and Adult Rat Models of Chemotherapy-Induced Alopecia

    January 2014 in “ Journal of Clinical and Investigative Dermatology ”
    Jimenez Joaquin J
    Studysummary This study observed that young rat models, with naturally synchronized hair growth phases, developed total alopecia after chemotherapy and may serve as a better model for testing CIA protective treatments compared to adult rats.
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    Research cited in this study 7

    1. Pathobiology of Chemotherapy-Induced Hair Loss The Lancet Oncology · 2013
    2. Permanent Alopecia After Systemic Chemotherapy: A Clinicopathological Study of 10 Cases The American Journal of Dermatopathology · 2011
    3. Chemotherapy-Induced Alopecia: Emotional Distress and Mitigation Strategies Seminars in Cutaneous Medicine and Surgery · 2009
    4. Protection Against Chemotherapy-Induced Alopecia Pharmaceutical Research · 2006
    5. A Guide to Assessing Damage Response Pathways of the Hair Follicle: Lessons From Cyclophosphamide-Induced Alopecia in Mice Journal of Investigative Dermatology · 2005
    6. Chronic Telogen Effluvium: Increased Scalp Hair Shedding in Middle-Aged Women Journal of The American Academy of Dermatology · 1996
    7. Chemotherapy-Induced Alopecia in Mice: Induction by Cyclophosphamide, Inhibition by Cyclosporine A, and Modulation by Dexamethasone PubMed · 1994