Introduction: Splintering Urbanism

Switching from finasteride to dutasteride led to increased hair loss and instability, even after returning to finasteride. Users suggest a gradual introduction of dutasteride while maintaining finasteride, and some recommend adding topical minoxidil and microneedling.

The conversation discusses switching from finasteride to dutasteride for hair loss treatment, with users sharing experiences and strategies for transitioning, such as alternating days or gradual introduction to avoid shedding. Some users report worsening hair conditions and side effects like low libido after switching.

David Barreto shared that a London-based research group is conducting a 12-month trial for a new nutraceutical treatment for pattern hair loss, designed with Dr. Carlos Puig. The trial aims to provide robust data, with results expected in 1-2 years, potentially representing a significant advancement since finasteride’s introduction in 1997.

Androgenetic alopecia is caused by DHT affecting hair growth. Finasteride and minoxidil are used to manage hair loss by blocking DHT and promoting hair growth.

Bryan Johnson uses a custom hair loss treatment that includes topical finasteride, minoxidil, azelaic acid, diclofenac, tea tree oil, rosemary oil, ginkgo biloba, biotin, and melatonin, which have shown varying degrees of effectiveness with minimal side effects. He also undergoes PRP and laser therapy, and has tried dutasteride mesotherapy.

Oral minoxidil is considered a safe and effective treatment for hair loss at low dosages, with minimal cardiac risks. Users report positive results, though some experience side effects like increased heart rate and skin changes, and consulting a doctor is advised.