Unraveling the Molecular Mechanism of Bider Marking Formation in Dun Mongolian Horses Through Transcriptome Sequencing

    April 2026 in “ Animals ”
    Tana An, Manglai Dugarjaviin
    Studysummary In this study, the researchers analyzed skin samples from Dun Mongolian horses to uncover molecular pathways linked to the "Bider" marking, identifying differential gene expression and several pigment-related signaling pathways that may play key roles in its formation.
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    Research cited in this study 10

    1. Differential Expression and Analysis of TBX3 Gene in Skin Tissues of Dun Mongolian Horses With and Without Bider Markings Animals · 2026
    2. Expression and Analysis of TBX3 Gene in the Skin from Three Locations on Dun Mongolian Bider Horse Genes · 2024
    3. Immune Niches for Hair Follicle Development and Homeostasis Frontiers in physiology · 2024
    4. Multi-Ancestry Tandem Repeat Association Study of Hair Color Using Exome-Wide Sequencing bioRxiv (Cold Spring Harbor Laboratory) · 2024
    5. PI3K-Akt-mTOR and Associated Signaling Pathways as Molecular Drivers of Immune-Mediated Inflammatory Skin Diseases: Update on Therapeutic Strategy Using Natural and Synthetic Compounds Cells · 2023
    6. A Comparative Study of Skin Transcriptomes and Histological Observations for Black and White Hair Colors of Giant Panda Frontiers in medicine · 2022
    7. Skin Transcriptome Reveals the Intrinsic Molecular Mechanisms Underlying Hair Follicle Cycling in Cashmere Goats Under Natural and Shortened Photoperiod Conditions Scientific reports · 2017
    8. Regulatory Pathway Analysis of Coat Color Genes in Mongolian Horses Hereditas · 2017
    9. Platelet-Derived Growth Factor Regulates the Proliferation and Differentiation of Human Melanocytes in a Differentiation-Stage-Specific Manner Journal of Dermatological Science · 2016
    10. Regulatory Mutations in TBX3 Disrupt Asymmetric Hair Pigmentation That Underlies Dun Camouflage Color in Horses Nature Genetics · 2015