80 citations
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January 1979 in “Journal of Surgical Oncology” This paper reviews keratoacanthoma as a tumor that resembles but rarely progresses to squamous cell carcinoma, detailing its stages, potential origins, and distinguishing features from other similar growths, without reporting new clinical results.
June 2026 in “BULLETIN OF STOMATOLOGY AND MAXILLOFACIAL SURGERY” This review summarizes the clinical, dermoscopic, and histopathological features of keratoacanthoma and discusses treatment strategies, emphasizing dermoscopy's role in diagnosis and individualized treatment planning.
January 1990 in “The Nishinihon Journal of Dermatology” This study suggests that keratoacanthomas may be distinguished from squamous cell carcinoma by identifying hair follicle structures, based on keratin expression and histological features observed in tumor samples.
2 citations
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March 1994 in “Oncology Reports” This study suggests that keratin expression in keratoacanthomas resembles that in the upper part of hair follicles, implying a potential origin, but it is indistinguishable from squamous cell carcinomas in terms of keratin reactivity.
January 2025 in “Dermatology Review” In this case report, a 57-year-old man with chronic myelogenous leukemia developed a large, rapidly growing giant keratoacanthoma, highlighting the diagnostic challenges it poses compared to cutaneous squamous cell carcinoma, with surgical excision identified as the preferred treatment.