Male Pattern Baldness and Its Association with Coronary Heart Disease: A Meta-Analysis

In this study, higher scores of HOMA-IR and FIRI suggested that male patients with early-onset androgenetic alopecia may have insulin resistance, although no significant differences in metabolic syndrome were found compared to controls.

This study found that men with early-onset androgenetic alopecia had a higher prevalence of metabolic syndrome and carotid atheromatous plaques than control subjects, suggesting a need for cardiovascular screening in this group.

This study found a significant association between androgenetic alopecia and metabolic syndrome, highlighting high-density lipoprotein cholesterol as a particularly important factor.

This study found a strong association between androgenetic alopecia and hypertension in Caucasian men, independent of age.

This study found a correlation between moderate to extensive alopecia and low-grade inflammation, a cardiovascular risk marker, particularly in young men under 35 with central obesity.

This review discusses the complexities of diagnosing and treating iron deficiency related to nutritional anemia and hair loss, concluding that routine screening and supplementation for hair loss are not yet supported by sufficient evidence.

This review discusses the diagnosis and treatment of iron deficiency, its potential link to hair loss, and emphasizes the importance for dermatologists to understand these aspects; it reports no new findings.

This article reviews the mechanisms by which minoxidil stimulates hair growth and reports no new clinical findings.

This study suggests a potential link between early-onset baldness before age 30 and increased risk for coronary artery disease, warranting consideration in epidemiological research.

This study found that men with early-onset androgenic alopecia have a higher risk of needing coronary revascularization before age 60 compared to those with later onset or no hair loss.

Early hair loss may indicate risk of insulin resistance.

This article discusses the treatment of androgenetic alopecia and alopecia areata with finasteride and minoxidil but reports no new clinical results.

This source notes that topical minoxidil and oral finasteride can modestly maintain or regrow hair in men with androgenic alopecia, especially at the scalp vertex, with minimal side effects.

This study found that dermal papilla cells from balding scalp hair follicles have significantly higher levels of androgen receptors than those from non-balding follicles, supporting their in vivo androgen response.

This review discusses the wide range of drugs potentially causing reversible or irreversible hair loss and emphasizes the difficulty of diagnosing drug-induced alopecia without withdrawal of the suspected medication; it reports no new clinical findings.

This review discusses various aspects of hair biology and pathology, including hair growth control, hair loss causes, and scalp conditions, and reports no clinical results.