The Role of Vitamin D in Alopecia Areata

January 2016 in “ Dermatology Review ”

Katarzyna M. Chyl-Surdacka, Agnieszka Gerkowicz, Grażyna Chodorowska

alopecia areata vitamin D autoimmune processes cytokine expression hair follicle antigens immune responses vitamin D receptor calcium homeostasis

TLDR Vitamin D might help treat alopecia areata.

Alopecia areata is an inflammatory disease characterized by noncicatricial hair loss, with its pathogenesis not fully understood. Recent research highlighted the role of autoimmune processes, evidenced by autoantibodies against hair follicle antigens and increased cytokine expression around hair follicles. Vitamin D, known for maintaining calcium homeostasis, also regulates immune responses through its receptor on various immune and hair follicle cells. It suppresses immune system activity, and its deficiency might contribute to alopecia areata's pathophysiology. The data from this period suggested that vitamin D supplementation could be a potential therapeutic option for patients with alopecia areata.

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research Vitamin D Deficiency in Alopecia Areata

105 citations , March 2014 in “British journal of dermatology/British journal of dermatology, Supplement”

Alopecia areata patients often have low vitamin D levels, suggesting they might benefit from vitamin D supplements.

research Reduced Level of 25-Hydroxyvitamin D in Chronic/Relapsing Alopecia Areata

40 citations , April 2013 in “Dermato-endocrinology”

People with chronic Alopecia Areata often have lower vitamin D levels.

research Alopecia Areata Update

85 citations , October 2012 in “Dermatologic Clinics”

Alopecia Areata is an autoimmune condition often starting before age 20, with varied treatment success and a need for personalized treatment plans.

research Vitamin D Concentrations Are Decreased in Patients with Alopecia Areata

54 citations , January 2012 in “Vitamins & Trace Elements”

People with Alopecia Areata have lower vitamin D levels.

research Successful Treatment of Alopecia Areata with Topical Calcipotriol

51 citations , January 2012 in “Annals of dermatology/Annals of Dermatology”

A boy with alopecia regrew hair using a vitamin D cream after other treatments failed.

research The Role of Vitamin D Receptor Mutations in the Development of Alopecia

109 citations , June 2011 in “Molecular and Cellular Endocrinology”

Vitamin D receptor mutations can cause alopecia by affecting hair growth genes.

research Does D Matter? The Role of Vitamin D in Hair Disorders and Hair Follicle Cycling

98 citations , February 2010 in “Dermatology Online Journal”

Vitamin D may help treat hair disorders.

research Lack of the Vitamin D Receptor Is Associated with Reduced Epidermal Differentiation and Hair Follicle Growth

180 citations , January 2002 in “The journal of investigative dermatology/Journal of investigative dermatology”

Vitamin D Receptor is crucial for normal skin and hair growth.

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Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment

community Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment

in Research 865 upvotes 1 year ago

The treatment for androgenetic alopecia involves using finasteride and minoxidil with intense exercise and cold exposure to boost metabolism and reduce androgenic effects, potentially leading to hair regrowth. This approach may activate biological pathways for improved hair and overall health.

community I bought a microscope, how does my scalp/hairs look? I've been suffering diffuse thinning and hair loss after covid and never recovered (2 yrs ago) I eat healthy, in shape and workout.

in Progress Pictures 87 upvotes 1 year ago

A person with hair loss since COVID-19 is considering treatments like finasteride and minoxidil but is hesitant due to potential side effects. Suggestions include visiting a dermatologist, using a ketoconazole shampoo, and considering that post-COVID hair loss might be an autoimmune response.

community I started rapidly diffuse thinning at 22. I'm 42 now and have as much hair as I did at 16. AMA

in Treatment 443 upvotes 5 years ago

Hair loss treatments like finasteride, minoxidil, ketoconazole, PRP, and microneedling helped maintain hair for 20 years. Research and try evidence-based treatments for best results.

community can someone please tell me its going to get better? im bawling my eyes out

in Female 67 upvotes 3 years ago

A 16-year-old girl is experiencing hair loss, which has worsened despite using minoxidil and multivitamins. Suggestions include broader hormone testing and considering other treatments like spironolactone if the hair loss is due to androgenic alopecia.

community To anyone that is still not seeing results on the big 3…

in Treatment 105 upvotes 3 years ago

User redh0t12 suggests using a derma pen for hair regrowth, as it helped them after using finasteride and minoxidil. Others discuss their experiences with various treatments, including derma rolling, oral and topical minoxidil, and finasteride, with mixed results.

community C’est terrible - at my wits end

in Female 450 upvotes 2 years ago

A 29-year-old woman is experiencing gradual hair thinning since age 15, suspects Androgenic Alopecia, and has tried 5% minoxidil with little success. She has purchased various hair loss treatments including minoxidil, dutasteride, finasteride, and spironolactone, but is cautious about starting them due to potential interactions with her ADHD medication.

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research Twenty Nail Dystrophy with Alopecia Areata in an Atopic Child

April 2019 in “International journal of research in dermatology”

A child with rough nails also had hair loss and allergies.