Vitamin D Deficiency in Patients With Alopecia Areata and Responsiveness to Vitamin D Analogues: A Systematic Review

    January 2024 in “ Journal of advanced research in Medical and Health science ”
    Mitchell R. Lie, Cut Bueleun Maulida Buket
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    Studysummary This study observed that vitamin D deficiency in alopecia areata correlates inversely with disease severity and duration, but does not correlate with serum vitamin D levels. Our plain-language summary of this paper — not a Tressless recommendation.
    The systematic review titled "Vitamin D Deficiency in Patients with Alopecia Aerata, and Responsiveness to Vitamin D Analogues" concluded that Vitamin D deficiency in alopecia aerata correlates inversely with disease severity and duration. The study also found that Vitamin D receptor expression is reduced in alopecia aerata and inversely correlates with inflammation histologically, but does not correlate with serum vitamin D levels, severity, pattern, or duration of illness. The review considered a total of 10 papers, including five research that met the criteria. The search for relevant studies was conducted on PubMed and SagePub databases, considering publications from 2013 to 2023.
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