August 2026 in “DOAJ (DOAJ: Directory of Open Access Journals)” This review summarizes the potential of exosome-based therapies as a promising treatment for androgenetic alopecia, emphasizing their role in modulating key signaling pathways, but highlights the need for further evidence to confirm their efficacy and safety.
November 2025 in “Journal of Craniofacial Surgery Open” This study highlights exosome-based therapies as promising treatments for androgenetic alopecia, detailing protocol development, quality control measures, and clinical application examples, with mesenchymal stem cell-derived exosomes improving hair density in a case study without adverse effects.
October 2025 in “Gene Expression” This review explores the potential of exosomes, which contain substances that may stimulate hair follicle activity, as a new therapeutic strategy for alopecia, and discusses their possible benefits and risks based on current knowledge of microRNAs and intracellular signaling in hair follicle morphogenesis.
December 2025 in “World Journal of Stem Cells” This study identified 232 stable proteins in exosomes from human adipose-derived mesenchymal stem cells and suggested a signaling axis that might support future androgenetic alopecia treatments.
July 2026 in “Periodontology 2000” This study reviewed exosome-mediated interventions for alopecia, finding that they enhance hair regeneration by stimulating key pathways and improving hair properties, with clinical studies showing increased hair density and patient satisfaction, though further trials are needed for widespread clinical use.