TLDR The child's body didn't respond well to vitamin D, causing hair loss and rickets.
The document described a case of an unusual form of vitamin D-dependent rickets in a child, characterized by alopecia and significant end-organ hyposensitivity to biologically active vitamin D. This condition indicated that despite the presence of active vitamin D, the child's body showed a reduced response, leading to symptoms such as hair loss and bone development issues typical of rickets. The study highlighted the complexity of vitamin D metabolism and its impact on both bone health and hair growth.
170 citations,
May 1979 in “The journal of pediatrics/The Journal of pediatrics” Two sisters with rickets and hair loss had a genetic issue with vitamin D processing, and only improved when given phosphorus supplements.
110 citations,
November 1984 in “The American Journal of Medicine” A genetic defect in vitamin D receptors causes severe rickets and hair loss in children, but some heal as they age.
6 citations,
August 1989 in “European journal of pediatrics” Child with rickets improved with a specific vitamin D therapy, but alopecia did not change.
50 citations,
October 1986 in “European journal of pediatrics” A boy with severe Vitamin D-resistant rickets did not respond to treatment and lacked a common symptom, suggesting a need for alternative treatments.
25 citations,
June 2019 in “Endocrine Related Cancer” Mutations in certain receptors can cause diseases and offer new treatment options.
4 citations,
March 2009 in “British Journal of Dermatology” The conference highlighted new dermatological treatments and emphasized early intervention and addressing conditions lacking evidence-based treatments.
