An Unusual Form of Vitamin D-Dependent Rickets in a Child: Alopecia and Marked End-Organ Hyposensitivity to Biologically Active Vitamin D

October 1980 in “ The Journal of Clinical Endocrinology & Metabolism ”

Yutaka Tsuchiya, Nobutake Matsuo, Hideo Cho, Mitio Kumagai, Atsushi Yasaka, T Suda, Hajime Orimo, Masataka Shiraki

vitamin D alopecia end-organ hyposensitivity biologically active vitamin D rickets vitamin D metabolism hair loss active vitamin D

TLDR The child's body didn't respond well to vitamin D, causing hair loss and rickets.

The document described a case of an unusual form of vitamin D-dependent rickets in a child, characterized by alopecia and significant end-organ hyposensitivity to biologically active vitamin D. This condition indicated that despite the presence of active vitamin D, the child's body showed a reduced response, leading to symptoms such as hair loss and bone development issues typical of rickets. The study highlighted the complexity of vitamin D metabolism and its impact on both bone health and hair growth.

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research Rickets With Alopecia: An Inborn Error of Vitamin D Metabolism

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