TLDR New therapies show promise for wound healing, but more research is needed for safe, affordable options.
The review discusses the challenges and advancements in regenerative medicine for wound healing, focusing on chronic wounds like diabetic ulcers. It highlights the potential of therapies such as growth factors, stem cells, and biomaterials to enhance tissue regeneration. Key molecular pathways, including TGF-ß, VEGF, Wnt/ß-catenin, and PI3K/AKT/mTOR, are crucial for processes like angiogenesis and cell proliferation. The review emphasizes the need for rigorous studies to ensure the safety and efficacy of these treatments and explores the economic impact of new technologies. Despite advancements, there is a need for cost-effective and safe alternatives, with future prospects including personalized therapies and wearable technologies to improve patient outcomes.
5 citations,
December 2021 in “Journal of Investigative Dermatology” Hedgehog signaling in certain cells is crucial for hair growth during wound healing.
119 citations,
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