Supplementary Material For: Tofacitinib In Overlapping Autoimmune And Autoinflammatory Disorders: A Case Report Of A Dual Graham-Little-Piccardi-Lasseur Syndrome And Hidradenitis Suppurativa
April 2026
in “
Figshare
”
New to Tofacitinib? There is a guide in the encyclopedia. Read the guide → 
Studysummary The researchers reported a case where treatment with tofacitinib improved both hair loss and skin lesions in a patient with Graham-Little-Piccardi-Lassueur Syndrome and hidradenitis suppurativa over six months, with no recurrence or adverse events during two-year follow-up. Our plain-language summary of this paper — not a Tressless recommendation.
This case report discusses a female patient with overlapping autoimmune disorders, Graham-Little-Piccardi-Lassueur Syndrome (GLPLS) and hidradenitis suppurativa (HS), characterized by scalp hair loss and follicular lesions. Traditional treatments were ineffective, leading to the administration of tofacitinib 5 mg twice daily. After six months, the patient showed significant improvement in hair loss and resolution of lesions, with no recurrence or adverse events over a two-year follow-up. The report highlights the potential effectiveness of the JAK inhibitor tofacitinib in treating these challenging conditions.
