Recovery of Nail Dystrophy: Potential New Therapeutic Indication of Tofacitinib

    February 2017 in “ Clinical rheumatology
    Jose A. Jaller, Juan José Jaller, Antonio M. Jaller, Juan J. Jaller-Char, Sineida Berbert Ferreira, Rachel Berbert Ferreira, Morton Scheinberg
    TLDR Tofacitinib may help treat nail dystrophy, especially when other treatments fail.
    The document reported that tofacitinib, a therapy initially developed for rheumatoid arthritis, showed potential benefits for patients with nail dystrophy, particularly those whose condition was resistant to conventional treatments. This finding suggested a new therapeutic indication for tofacitinib in treating nail diseases associated with autoimmune conditions like psoriasis and psoriatic arthritis.
    Discuss this study in the Community →

    Research cited in this study

    6 / 6 results

    Related Community Posts Join

    6 / 11 results

      community IGE Hair Loss and Miniaturization

      in Chat  3 upvotes 4 months ago
      A 23-year-old male is experiencing diffuse hair loss and miniaturization, possibly due to high IGE levels after using tofacitinib. He seeks advice and has not yet consulted a dermatologist.

      community Topical solution recommendation

      in Treatment  1 upvotes 2 weeks ago
      The user is using finasteride 1mg every other day and seeks a topical solution excluding minoxidil. They are considering various combinations of ingredients like finasteride, dutasteride, and tofacitinib, with options for nourishing oils and other additives.

      community Topical solution recommendation

      in Product  1 upvotes 2 weeks ago
      The user is using finasteride 1mg every other day and seeks a topical solution to complement it, excluding minoxidil. They are considering various combinations of ingredients like finasteride, dutasteride, and tofacitinib, with options for nourishing oils and other additives.

      community 22F. Should I even bother getting a biopsy? Is there any point?

       6 upvotes 9 years ago
      A woman who has been experiencing hair loss for several years, and her question of whether there is any benefit to getting a biopsy to check if it's AGA or diffuse alopecia areata when no cure or very effective treatment exists. Treatments such as spironolactone and Minoxidil/finasteride/RU58841 have previously been discussed.

      community No hair, don't care! [24/F] :)

       61 upvotes 9 years ago
      A woman with alopecia universalis shares her positive experience of being bald, finding it freeing and less worrisome. She also discusses her skincare routine using Korean products.

    Similar Research

    5 / 762 results