Thyroid Functions in Patients With Diffuse Hair Loss

October 2022 in “ The Egyptian Journal of Hospital Medicine ”

Dounia Mammar Kebbab, Samia Mohamed El-said Abd El-Naby, Sara Hamdy Fouad, Khadiga Mohamed El-Hamaky Hasanin

diffuse hair loss thyroid dysfunctions thyroid-stimulating hormone TSH thyroxine free FT4 hyperthyroidism overt hypothyroidism subclinical hypothyroidism

TLDR Diffuse hair loss in women is often linked to thyroid problems.

The study "Thyroid Functions in Patients with Diffuse Hair Loss" conducted on 120 female patients with diffuse hair loss and 60 healthy controls found a significant correlation between thyroid dysfunctions and diffuse hair loss. The study revealed a statistically significant difference in thyroid-stimulating hormone (TSH) concentrations between the two groups of patients (P<0.001), with higher TSH concentrations in the group with associated systemic disease. However, there was no significant difference in thyroxine free (FT4) levels between the two groups. Among the patients with associated systemic disease, 16.6% had thyroid disorders, including 3.33% with hyperthyroidism, 6.66% with overt hypothyroidism, and 6.66% with subclinical hypothyroidism. The study concluded that abnormal thyroid functions were present in a significant number of cases of diffuse hair loss, suggesting the need for thyroid function investigations in all cases of adult women with diffuse hair loss.

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