Effects of Thioglycolate Compounds in an Emerging Technique in the World of Cosmetics—Brow Lamination

October 2024 in “ Journal of Cosmetic Dermatology ”

Laura Ghanem, Stephani Chagoury, Andrea Issa, K Khoury, Kelly Katherine Karam, Milissa Makhlouf

ammonium thioglycolate thioglycolic acid brow lamination allergic contact dermatitis skin irritation eyebrow hair structure pigmentation changes transdermal absorption endocrine system effects ATG TGA

Studysummary This study highlights that chemicals used in brow lamination, like ammonium thioglycolate and thioglycolic acid, may cause skin irritation and other systemic issues, suggesting a need for further investigation and regulatory measures. Our plain-language summary of this paper — not a Tressless recommendation.

This study investigates the side effects of ammonium thioglycolate (ATG) and thioglycolic acid (TGA), key ingredients in brow lamination, a popular cosmetic technique. The hydrophilic nature of these compounds allows for transdermal absorption, potentially causing allergic contact dermatitis, skin irritation, and changes in eyebrow hair structure and pigmentation. Additionally, systemic effects on the reproductive, ocular, respiratory, and endocrine systems are possible. The study concludes that further research and regulation are necessary to minimize these side effects and ensure safe use of these chemicals in cosmetics.

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