TLDR Botulinum neurotoxin A is effective and safe for treating various conditions, but more clinical trials are needed to fully assess its benefits and risks.
The review explores the non-cosmetic uses of botulinum neurotoxin A (BTX-A) in clinical practice, highlighting its effectiveness and safety. BTX-A is effective for treating idiopathic hyperhidrosis, with effects lasting up to 44 months when combined with oxybutynin hydrochloride. It may also be optimal for treating androgenic alopecia, especially when used with finasteride and minoxidil. Additionally, BTX-A successfully treats facial rosacea and severe atopic dermatitis with associated pruritus without significant side effects. However, due to a lack of clinical trials, the benefit-risk ratio of BTX-A for these conditions cannot be objectively assessed.
June 2022 in “Journal of Cosmetic Dermatology” Adding botulinum toxin A to standard hair loss treatments improves hair growth.
13 citations
,
May 2020 in “Journal of Plastic Reconstructive and Aesthetic Surgery” Botulinum toxin's effectiveness for treating scalp alopecia is not well-supported due to insufficient data.
15 citations
,
April 2020 in “Journal of The American Academy of Dermatology” Botulinum toxin injections may help treat hair loss by blocking harmful secretion in hair follicles.
15 citations
,
January 2020 in “BioMed Research International” BTA safely and effectively treats hair loss, and works better with FNS.
53 citations
,
January 2017 in “Skin appendage disorders” Botulinum toxin shows promise for various skin conditions but requires more research for confirmation and standardized use.
5 citations
,
May 2022 in “Molecules” Botulinum toxin is effective for various skin conditions, but more research and awareness of side effects are needed.
Botulinum toxin shows promise for treating scalp sweating but not for hair growth.
1 citations
,
May 2008 in “Toxicon” The lowest effective dose of Botox for detrusor sphincter dyssynergia is between 75-100 units.
19 citations
,
November 2011 Using systemic drugs as creams for skin conditions shows promise, but more research is needed to confirm their effectiveness and safety.