The importance of dual 5α-reductase inhibition in the treatment of male pattern hair loss: Results of a randomized placebo-controlled study of dutasteride versus finasteride
December 2006
in “Journal of The American Academy of Dermatology”
TLDR Dutasteride more effective for hair growth, but has more side effects than finasteride.
A study from 2006 compared the effectiveness of dutasteride and finasteride, both 5α-reductase inhibitors, in treating male pattern hair loss (MPHL). The study involved 416 men and found that dutasteride was more effective than finasteride in promoting hair growth and reducing hair loss. However, dutasteride also had more side effects than finasteride. The study suggests that dual 5α-reductase inhibition is important in treating MPHL and that dutasteride may be a more effective treatment option than finasteride.
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Cited in this study
research Immunohistochemical localization of types 1 and 2 5α-reductase in human scalp
The study found that two enzymes linked to hair loss are located in different parts of the scalp, supporting a common treatment's effectiveness.
research Finasteride in the treatment of men with androgenetic alopecia
Finasteride safely and effectively treats male pattern hair loss, but may cause reversible sexual issues and harm male fetuses.
research Fortnightly review: Male pattern androgenetic alopecia
Hair loss in men is common, treatable, but not curable.
research Male pattern hair loss: current understanding
Genetics and hormones cause hair loss; finasteride treats it safely.
research Different Levels of 5α-Reductase Type I and II, Aromatase, and Androgen Receptor in Hair Follicles of Women and Men with Androgenetic Alopecia
People with hair loss have more androgen receptors and enzymes in certain follicles, with men and women showing different patterns.
research PHOTOGRAPHIC DOCUMENTATION OF HAIR GROWTH IN ANDROGENETIC ALOPECIA
Photographic documentation crucial for evaluating hair growth in androgenetic alopecia.
research The effect of finasteride, a 5 alpha-reductase inhibitor, on scalp skin testosterone and dihydrotestosterone concentrations in patients with male pattern baldness
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research Pharmacological therapeutics in androgenetic alopecia
research Finasteride in The Treatment of Female Androgenic Alopecia
Finasteride may help postmenopausal women with hair loss but is not effective for all and should be used cautiously in premenopausal women.
research 한국인의 두피모발 특성과 남성형탈모증
The document's conclusion cannot be provided because the text is in Korean and cannot be parsed.
research The importance of dual 5α-reductase inhibition in the treatment of male pattern hair loss: Results of a randomized placebo-controlled study of dutasteride versus finasteride
Dutasteride more effective for hair growth, but has more side effects than finasteride.
research Effective treatment of female androgenic alopecia with dutasteride.
Dutasteride successfully treated a woman's hair loss when other treatments failed.
research The effects of finasteride on scalp skin and serum androgen levels in men with androgenetic alopecia
Finasteride effectively reduces hair loss by decreasing androgen levels.
research The effect of finasteride, a 5 alpha-reductase inhibitor, on scalp skin testosterone and dihydrotestosterone concentrations in patients with male pattern baldness.
Finasteride reduces scalp DHT levels, potentially treating male pattern baldness.
research The effect of finasteride, a 5 alpha-reductase inhibitor, on scalp skin testosterone and dihydrotestosterone concentrations in patients with male pattern baldness
research Effect of finasteride, a 5 alpha-reductase inhibitor, on serum gonadotropins in normal men.
Finasteride doesn't affect hormone levels in normal men.