Spotlight in Plastic Surgery: October 2022

    September 2022 in “ Plastic and Reconstructive Surgery
    Brett T. Phillips, Mario Alessandri‐Bonetti, Murad J. Karadsheh, Aneesh Karir, Siddharth Mendiratta, Kerry A. Morrison, Miguel Ribeiro Matias, Tyler Safran, Benjamin R. Slavin, Yoshiko Toyoda, Otto R Ziegler Rodríguez, Arun K. Gosain
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    TLDR Baricitinib helps with severe hair loss, negative-pressure therapy lowers hernia recurrence, tranexamic acid reduces bleeding, robot-assisted breast surgery may improve outcomes, and acellular dermal matrix could decrease breast reconstruction complications.
    The "Spotlight in Plastic Surgery: October 2022" review discusses several studies related to plastic surgery. A study involving 1200 patients found that baricitinib, an oral JAK1 and JAK2 inhibitor, was more effective than a placebo in treating severe alopecia areata, suggesting its potential for hair restoration treatments. Another study with 114 patients showed that negative-pressure wound therapy reduced hernia recurrence rates in patients having ventral hernia repair with panniculectomy. A study of 9535 patients demonstrated that tranexamic acid safely reduced bleeding in noncardiac surgery, supporting its growing use in plastic surgery procedures. A retrospective review of 73 women indicated that robot-assisted nipple-sparing mastectomy and reconstruction could increasingly replace traditional open surgery due to better cosmetic outcomes and similar complication rates. Finally, a study of over 9500 patients found that long-term acellular dermal matrix might be linked with less capsular contracture and fewer implant complications in breast reconstruction.
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