Spanlastics: An Innovative Nanovesicular Platform for Advanced Drug Delivery
December 2025
in “
Journal of Drug Discovery and Therapeutics
”
TLDR Spanlastics improve drug delivery by enhancing bioavailability and targeting, reducing side effects.
Spanlastics are an innovative nanovesicular platform designed to improve drug delivery by addressing the limitations of traditional formulations like liposomes and nanoparticles. These elastic, non-toxic vesicles can encapsulate drugs, offering controlled and targeted delivery, which enhances the bioavailability of poorly soluble drugs and provides better stability. Spanlastics are effective in delivering both hydrophilic and lipophilic drugs to specific sites, thereby reducing side effects and improving therapeutic outcomes. The review discusses the classification, preparation methods, mechanisms, evaluation techniques, and various applications of spanlastics in modern drug delivery systems.