Smart Biomaterials and Dressings for the Treatment of Chronic Inflammatory Skin Diseases

    December 2025 in “ Rare Metals
    Zehao Lan, Shengjie Xue, Junyi Yin, Shaolei Wang, Tianke Zhu, Jieyue Liao
    TLDR Smart biomaterials and dressings show promise in treating chronic skin diseases by improving drug delivery and minimizing side effects.
    The review explores the potential of smart biomaterials and dressings in treating chronic inflammatory skin diseases, affecting over 30% of the global population. These advanced dressings, including photo-, ultrasound-, and water-responsive types, offer spatiotemporal control of drug delivery, adapting to disease fluctuations and minimizing adverse effects. They utilize stimuli-responsive materials to enhance treatment efficacy for conditions like psoriasis, acne, and infections, with some showing promise in promoting hair growth, suggesting applications in alopecia treatment. Future directions involve developing multi-stimuli responsive materials and integrating AI-driven drug adjustment algorithms. Despite promising results in animal models, challenges remain in translating these technologies to human applications, ensuring pathogen specificity, and managing costs.
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